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Research article

First published 2010-4

An Efficient Improvement on Total Synthesis of Shikonin

Zhen Rao, Wen Zhou, Ying Peng [...]

Journal of Chemical Research

Open access

Research article

First published 2020-4

Investigating the Effects of Shikonin,Deoxyshikonin,and (β,β-Dimethylacryl)Shikonin on Melanoma Cell Lines

Jin Jie Dillon Ng, Zee Upton, David Leavesley [...]

Natural Product Communications

Open access

Research article

First published 2021

Shikonin Inhibits Cholangiocarcinoma Cell Line QBC939 by Regulating Apoptosis,Proliferation,and Invasion

Chang Liu, Li-Qian Xuan, Kai Li [...]

Cell Transplantation

Open access

Research article

First published 2024-05

Deucravacitinib and shikonin combination therapy ameliorates imiquimod-induced psoriasis in mice

Ling Xu, Ying Jiang, Fuping Xu [...]

International Journal of Immunopathology and Pharmacology

Open access

Research article

First published 2026

Shikonin improves intestinal barrier function through modulation of GPX4 expression in intestinal epithelial cells

Fuheng Yang, Peihua Liang, Hengli Guo [...]

International Journal of Immunopathology and Pharmacology

Open access

Research article

First published 2024-6

The Anti-tumor Function of Shikonin by Targeting EGFR/AKT/mTOR Signaling in Human Osteosarcoma Cells

Rui-Dan Zhu, Jia-Jia Zhang, Xiao-Bin Yao [...]

Pharmacognosy Magazine

Open access

Research article

First published 2024-9

Shikonin Attenuate Behavioral Defects,Oxidative Stress,and Neuroinflammation During Aluminum Chloride-induced Alzheimer’s Disease Condition in an in vivo Experimental Model

Danni Li, Min Wang

Pharmacognosy Magazine

Open access

Research article

First published 2025-10

Omarigliptin/shikonin combination alleviates cyclosporine-induced nephrotoxicity: The role of sirtuin 1,glucagon-like peptide-1,HMGB1/RAGE/TLR4 signaling,and p38/ERK/JNK MAPKs

Marwa H. Abdallah, Hanan Abdelmawgoud Atia, Hemat A. Elariny [...]

Human & Experimental Toxicology

Open access

Research article

First published 2021-9

A new synthetic method toward a key intermediate in the total synthesis of alkannin and shikonin

Xiaogang Zheng, Hang Hu, Defeng Xu

Journal of Chemical Research

Open access

Research article

First published 2021-7

Effects of shikonin on the development of ovarian follicles and female germline stem cells

Shu-Xin Ma, Li-Bo Tang, Zhi-Hang Chen [...]

Journal of International Medical Research

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