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Research article

First published 2015-8

Application of Parallel Multiparametric Cell-Based FLIPR Detection Assays for the Identification of Modulators of the Muscarinic Acetylcholine Receptor 4 (M 4 )

Emery Smith, Peter Chase, Colleen M. Niswender [...]

Journal of Biomolecular Screening

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Research article

First published 2017-9

High-Throughput Agonist Shift Assay Development for the Analysis of M 1 -Positive Allosteric Modulators

Michelle F. Homsher, Douglas C. Beshore, Jason Cassaday [...]

Journal of Biomolecular Screening

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Research article

First published 2015-4

Pharmacokinetic and pharmacodynamic characterisation of JNJ-40411813,a positive allosteric modulator of mGluR2,in two randomised,double-blind phase-I studies

Hiba Salih, Ion Anghelescu, Iva Kezic [...]

Journal of Psychopharmacology

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Research article

First published 2012-4

Design of an Automated Enhanced-Throughput Platform for Functional Characterization of Positive Allosteric Modulator-Induced Leftward Shifts in Apparent Agonist Potency In Vitro

Adam Hendricson, Michele Matchett, Meredith Ferrante [...]

Journal of Laboratory Automation

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Research article

First published 2014-10

Identification of Selective Agonists and Positive Allosteric Modulators for µ- and δ-Opioid Receptors from a Single High-Throughput Screen

Neil T. Burford, Tom Wehrman, Daniel Bassoni [...]

Journal of Biomolecular Screening

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Research article

First published 2014-3

Determining the Relative Efficacy of Positive Allosteric Modulators of the GABA A Receptor

Philippe Ghisdal, Nadine Noel, Nathalie Pacico [...]

Journal of Biomolecular Screening

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Research article

First published 2014-7

A Duplexed High-Throughput Screen to Identify Allosteric Modulators of the Glucagon-Like Peptide 1 and Glucagon Receptors

Lindsey C. Morris, Emily L. Days, Maxine Turney [...]

Journal of Biomolecular Screening

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Research article

First published 2015-10

High-Throughput Screening for Positive Allosteric Modulators Identified Potential Therapeutics against Acetylcholinesterase Inhibition

Richard R. Chapleau, Craig A. McElroy, Christopher D. Ruark [...]

Journal of Biomolecular Screening

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Research article

First published 2017-4

First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics,safety,and evidence for neurocognitive effect of AVL-3288

Kelvin W Gee, Ann Olincy, Richard Kanner [...]

Journal of Psychopharmacology

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Research article

First published 2016-12

Identification of Positive Allosteric Modulators of Glycine Receptors from a High-Throughput Screen Using a Fluorescent Membrane Potential Assay

Clara Stead, Adam Brown, Cathryn Adams [...]

Journal of Biomolecular Screening

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