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Research article

First published 2016-5

Nonclinical Safety Profile of Etelcalcetide,a Novel Peptide Calcimimetic for the Treatment of Secondary Hyperparathyroidism

Mark R. Fielden, Charles Dean, Kurt Black [...]

International Journal of Toxicology

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Research article

First published 2021-10

Nonclinical Safety Profile of Sotorasib,a KRAS G12C -Specific Covalent Inhibitor for the Treatment of KRAS p.G12C -Mutated Cancer

Katsu Ishida, Jonathan A. Werner, Rhian Davies [...]

International Journal of Toxicology

Open access

Review article

First published 2018-10

The Nonclinical Safety Profile of GalNAc-conjugated RNAi Therapeutics in Subacute Studies

Maja M. Janas, Carole E. Harbison, Victoria K. Perry [...]

Toxicologic Pathology

Open access

Research article

First published 2020-02

Nonclinical Safety Profile of Revusiran,a 1st-Generation GalNAc-siRNA Conjugate for Treatment of Hereditary Transthyretin-Mediated Amyloidosis

Jessica E. Sutherland, Julia L. Hettinger, Amy Chan [...]

Nucleic Acid Therapeutics

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Research article

First published 2014-5

Nonclinical Safety Profile of BMS-986001,a Nucleoside Transcriptase Inhibitor for Combination Retroviral Therapy

Guha Mausumee, Simutis Frank, Clark Shawn [...]

International Journal of Toxicology

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Research article

First published 2022

Scientific and Regulatory Policy Committee Points to Consider: Integration of Clinical Pathology Data With Anatomic Pathology Data in Nonclinical Toxicology Studies

William Siska, Albert Eric Schultze, Daniela Ennulat [...]

Toxicologic Pathology

Retricted access

Research article

First published 2007-06

Nonclinical Pharmacodynamics,Pharmacokinetics,and Safety of BOL-303224-A,a Novel Fluoroquinolone Antimicrobial Agent for Topical Ophthalmic Use

Keith W. Ward, Jean-François Lepage, Jean-Yves Driot

Journal of Ocular Pharmacology and Therapeutics

Retricted access

Meeting report

First published 2025-12

Neuro Omics: Translational Neuropathology Applications of Spatial Technologies From Nonclinical Models to Human Disease

Dinesh S. Bangari, Saravanan Kaliyaperumal, Nathaniel Roscoe [...]

Toxicologic Pathology

Free access

Review article

First published 2024-10

Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity,Drug Abuse Liability,and Pediatric Safety

Thulasi Ramani, Ronald L. Wange, T. Scott Manetz [...]

International Journal of Toxicology

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Research article

First published 2008-7

Nonclinical Aspects of Biopharmaceutical Development: Discussion of Case Studies at a PhRMA-FDA Workshop

L. A. Buckley, K. Benson, K. Davis-Bruno [...]

International Journal of Toxicology

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