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Article commentary

First published 2021-1

Hormesis Shifts the No-Observed-Adverse-Effect Level (NOAEL)

Evgenios Agathokleous, Costas Saitanis, Athina Markouizou

Dose-Response

Free access

Research article

First published 2013-2

Embracing a Weight-of-Evidence Approach for Establishing NOAELs for Nanoparticle Inhalation Toxicity Studies

David B. Warheit, Kenneth L. Reed, Michael P. DeLorme

Toxicologic Pathology

Free access

Review article

First published 2022-3

Practical Considerations in Determining Adversity and the No-Observed-Adverse-Effect-Level (NOAEL) in Nonclinical Safety Studies: Challenges,Perspectives and Case Studies

Vijay P. Kale, Ilona Bebenek, Hanan Ghantous [...]

International Journal of Toxicology

Retricted access

Research article

First published 2016-3

Evaluation of Safety Profiles of Blood Cancer Drugs Approved in Japan

Sachie Kubota, Kazuyuki Saito, Shunsuke Ono [...]

Therapeutic Innovation & Regulatory Science

Free access

Research article

First published 2023-1

Toxicologic Pathology Forum: Opinion on Approaches for Reporting Toxic and Adverse Dose Levels in Nonclinical Toxicology Studies Supporting the Development of Anticancer Pharmaceuticals

Renee R. Hukkanen, Tomoyuki Moriyama, Daniel J. Patrick [...]

Toxicologic Pathology

Free access

Research article

First published 2016-2

Scientific and Regulatory Policy Committee

Roy Kerlin, Brad Bolon, John Burkhardt [...]

Toxicologic Pathology

Open access

Research article

First published 2015-10

Threshold for Radon-Induced Lung Cancer From Inhaled Plutonium Data

Jerry M. Cuttler, Charles L. Sanders

Dose-Response

Retricted access

Research article

First published 2014-7

Consideration of Factors Affecting the Safety Index in Early Clinical Drug Development

Makoto Kayama, Mamoru Narukawa

Therapeutic Innovation & Regulatory Science

Free access

Research article

First published 2015-5

A 4-Week Toxicity Study of Methionine in Male Rats

Keigi Chin, Sakino Toue, Yasuko Kawamata [...]

International Journal of Toxicology

Free access

Research article

First published 2020-9

Toxicology Paradise: Sorting Out Adverse and Non-adverse Findings in Animal Toxicity Studies

Paul Baldrick, Mary Ellen Cosenza, Tessie Alapatt [...]

International Journal of Toxicology

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