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Research article

First published 2013-12

Building Predictive Models for Mechanism-of-Action Classification from Phenotypic Assay Data Sets

Ellen L. Berg, Jian Yang, Mark A. Polokoff

Journal of Biomolecular Screening

Open access

Research article

First published 2020-8

High-Content Phenotypic Profiling in Esophageal Adenocarcinoma Identifies Selectively Active Pharmacological Classes of Drugs for Repurposing and Chemical Starting Points for Novel Drug Discovery

Rebecca E. Hughes, Richard J. R. Elliott, Alison F. Munro [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2013-12

Clinical Relevance of Target Identity and Biology

Anand C. Patel

Journal of Biomolecular Screening

Open access

Research article

First published 2019-3

Evaluation of Machine Learning Classifiers to Predict Compound Mechanism of Action When Transferred across Distinct Cell Lines

Scott J. Warchal, John C. Dawson, Neil O. Carragher

Journal of Biomolecular Screening

Free access

Research article

First published 2011-2

A Quantitative,Facile,and High-Throughput Image-Based Cell Migration Method Is a Robust Alternative to the Scratch Assay

Wendy Gough, Keren I. Hulkower, Renee Lynch [...]

Journal of Biomolecular Screening

Open access

Research article

First published 2020-9

Resistance to paclitaxel induces glycophenotype changes and mesenchymal-to-epithelial transition activation in the human prostate cancer cell line PC-3

Leonardo Marques da Fonseca, Danilo Macedo Calvalhan, Jose Osvaldo Previato [...]

Tumor Biology

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Research article

First published 2013-12

The Contribution of Mechanistic Understanding to Phenotypic Screening for First-in-Class Medicines

David C. Swinney

Journal of Biomolecular Screening

Free access

Research article

First published 2011-1

The Tumor Suppressor,p190RhoGAP,Differentially Initiates Apoptosis and Confers Docetaxel Sensitivity to Breast Cancer Cells

Kirsten Ludwig, Sarah J. Parsons

Genes & Cancer

Retricted access

Research article

First published 2006-04

A Morphology- and Kinetics-Based Cascade for Human Neural Cell High Content Screening

Gillian R. Richards, Alison J. Smith, Frances Parry [...]

ASSAY and Drug Development Technologies

Free access

Research article

First published 2012-9

Development of a High-Content Screening Assay Panel to Accelerate Mechanism of Action Studies for Oncology Research

Danli L. Towne, Emily E. Nicholl, Kenneth M. Comess [...]

Journal of Biomolecular Screening

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