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Retricted access

Research article

First published 2017-07

Development of Three Orthogonal Assays Suitable for the Identification and Qualification of PIKfyve Inhibitors

Kylie Fogarty, Mohammed Kashem, Andras Bauer [...]

ASSAY and Drug Development Technologies

Free access

Research article

First published 2012-6

Screening and Characterization of Human Monoglyceride Lipase Active Site Inhibitors Using Orthogonal Binding and Functional Assays

José C. Clemente, Erica Nulton, Marina Nelen [...]

Journal of Biomolecular Screening

Open access

Review article

First published 2021-8

Brief Guide: Experimental Strategies for High-Quality Hit Selection from Small-Molecule Screening Campaigns

Ina Rothenaigner, Kamyar Hadian

Journal of Biomolecular Screening

Open access

Research article

First published 2025-02

Bioanalytical Assays for Oligonucleotide Therapeutics: Adding Antibody-Based Immunoassays to the Toolbox as an Orthogonal Approach to LC-MS/MS and Ligand Binding Assays

David P. Chimento, Amy L. Anderson, Inês Fial [...]

Nucleic Acid Therapeutics

Free access

Research article

First published 2021-12

The Impact of Assay Design on Medicinal Chemistry: Case Studies

Joshua R. Born, Vinoth Kumar Chenniappan, Danielle P. Davis [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2011-8

Multiplexed Reporter Gene Assays: Monitoring the Cell Viability and the Compound Kinetics on Luciferase Activity

Marie-Cecile Didiot, Sergio Serafini, Martin J. Pfeifer [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2016-05

Development and Validation of a Universal High-Throughput UDP-Glycosyltransferase Assay with a Time-Resolved FRET Signal

Thomas Zielinski, Melvin Reichman, Preston S. Donover [...]

ASSAY and Drug Development Technologies

Free access

Research article

First published 2008-06

Screening for Antiviral Inhibitors of the HIV Integrase—LEDGF/p75 Interaction Using the AlphaScreen™ Luminescent Proximity Assay

Yan Hou, Debra E. Mcguinness, Andrew J. Prongay [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2018-3

Development of an Inhibitor Screening Assay for Mono-ADP-Ribosyl Hydrolyzing Macrodomains Using AlphaScreen Technology

Teemu Haikarainen, Mirko M. Maksimainen, Ezeogo Obaji [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2010-4

AlphaScreen ® -Based Characterization of the Bifunctional Kinase/RNase IRE1α

Marion Bouchecareilh, Marie-Elaine Caruso, Philippe Roby [...]

Journal of Biomolecular Screening

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