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Research article

First published 2020-04-03

The Novel Dual GLP-1/GIP Receptor Agonist DA-CH5 Is Superior to Single GLP-1 Receptor Agonists in the MPTP Model of Parkinson’s Disease

Lingyu Zhang, Liping Zhang, Yanwei Li [...]

Journal of Parkinson’s Disease

Open access

Research article

First published 2020

Long-term outcomes of monascin – a novel dual peroxisome proliferator-activated receptor γ/nuclear factor-erythroid 2 related factor-2 agonist in experimental intracerebral hemorrhage

Pengcheng Fu, Jiachen Liu, Qinqin Bai [...]

Therapeutic Advances in Neurological Disorders

Open access

Research article

First published 2026-4

The Role of EP3 Agonism in Intraocular Pressure-Lowering by Sepetaprost,a Novel Dual Agonist of FP and EP3 Receptors,in Monkeys

Kentaro Maki, Erika Kimura, Yasuko Yamamoto [...]

Journal of Ocular Pharmacology and Therapeutics

Free access

Research article

First published 2014-11

The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db / db mice without peroxisome proliferator-activated receptor gamma–associated adverse cardiac effects

Rémy Hanf, Lesley J Millatt, Bertrand Cariou [...]

Diabetes & Vascular Disease Research

Open access

Review article

First published 2022

Glucagon-Like Peptide-1 Receptor Agonists and Dual Glucose-Dependent Insulinotropic Polypeptide/Glucagon-Like Peptide-1 Receptor Agonists in the Treatment of Obesity/Metabolic Syndrome,Prediabetes/Diabetes and Non-Alcoholic Fatty Liver Disease—Current Evidence

Emir M. Muzurović, Špela Volčanšek, Karin Zibar Tomšić [...]

Journal of Cardiovascular Pharmacology and Therapeutics

Open access

Research article

First published 2020

The Dual GLP-1/GIP Receptor Agonist DA4-JC Shows Superior Protective Properties Compared to the GLP-1 Analogue Liraglutide in the APP/PS1 Mouse Model of Alzheimer’s Disease

Mark Maskery, Elizabeth Mary Goulding, Simon Gengler [...]

American Journal of Alzheimer's Disease & Other Dementias®

Open access

Brief report

First published 2011-1

mGlu2 Metabotropic Glutamate Receptors Restrain Inflammatory Pain and Mediate the Analgesic Activity of Dual mGlu2/mGlu3 Receptor Agonists

Magda Zammataro, Santina Chiechio, Michael C Montana [...]

Molecular Pain

Open access

Research article

First published 2017-3

Aleglitazar,a dual peroxisome proliferator-activated receptor-α and -γ agonist,protects cardiomyocytes against the adverse effects of hyperglycaemia

Yan Chen, Hongmei Chen, Yochai Birnbaum [...]

Diabetes & Vascular Disease Research

Free access

Research article

First published 2024-9

Risk of major adverse cardiovascular events and stroke associated with treatment with GLP-1 or the dual GIP/GLP-1 receptor agonist tirzepatide for type 2 diabetes: A systematic review and meta-analysis

Maria-Ioanna Stefanou, Aikaterini Theodorou, Konark Malhotra [...]

European Stroke Journal

Open access

Review article

First published 2025

The dual impact of GLP-1 receptor agonists on metabolic and reproductive health in polycystic ovary syndrome: insights from human and animal trials

Bassel H. Hoteit, Jana Kotaich, Hadi Ftouni [...]

Therapeutic Advances in Endocrinology and Metabolism

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