Sage Journals: Discover world-class research

Retricted access

Research article

First published 2006-6

The Potential Role of Roflumilast: The New Phosphodiesterase-4 Inhibitor

Sarah B Karish, James M Gagnon

Annals of Pharmacotherapy

Open access

Case report

First published 2025

Phosphodiesterase-4 inhibition in localized scleroderma: A case series of topical roflumilast

Ghassan Barnawi, Alexandra Carla Bobica, Hessah BinJadeed [...]

Sage Open Medical Case Reports

Open access

Research article

First published 2018-11

Synergistic effect of phosphodiesterase 4 inhibitor and serum on migration of endotoxin-stimulated macrophages

Jing-Xing Yang, Te-Chih Hsiung, Fu-Chun Weng [...]

Innate Immunity

Open access

Review article

First published 2011

Roflumilast,a Novel Phosphodiesterase 4 Inhibitor,for COPD Patients with a History of Exacerbations

Stephen K. Field

Therapeutic Advances in Pulmonary and Critical Care Medicine

Open access

Research article

First published 2025-4

Effectiveness and safety of topical phosphodiesterase 4 inhibitors in children with mild-to-moderate atopic dermatitis: A systematic review and meta-analysis

Long Wang, Lequ Zeng, Yuyu Wu [...]

Journal of International Medical Research

Retricted access

Research article

First published 2006-10

Cilomilast: Orally Active Selective Phosphodiesterase-4 Inhibitor for Treatment of Chronic Obstructive Pulmonary Disease

Shaunta' D Martina, Maha S Ismail, Kimi S Vesta

Annals of Pharmacotherapy

Retricted access

Other

First published 2009-10

Treatment with the phosphodiesterase type-4 inhibitor rolipram fails to inhibit blood—brain barrier disruption in multiple sclerosis

Bibiana Bielekova, Nancy Richert, Thomas Howard [...]

Multiple Sclerosis Journal

Free access

Research article

First published 2010-6

Myocardial and Reproductive System Toxicity of SCH 351591,a Selective Phosphodiesterase-4 Inhibitor,in CD-1 Mice

Patricia E. Losco, Frederique M. Poulet, Grazyna Z. Kaminska-McNamara [...]

Toxicologic Pathology

Free access

Research article

First published 2019-7

[ 11 C]( R )-Rolipram positron emission tomography detects DISC1 inhibition of phosphodiesterase type 4 in live Disc1 locus-impaired mice

Maarten Ooms, Tetsuya Tsujikawa, Talakad G Lohith [...]

Journal of Cerebral Blood Flow & Metabolism

Free access

Research article

First published 2007-11

A Novel Phosphodiesterase Type 4 Inhibitor,HT-0712,Enhances Rehabilitation-Dependent Motor Recovery and Cortical Reorganization After Focal Cortical Ischemia

Erin MacDonald, Heidi Van der Lee, David Pocock [...]

Neurorehabilitation and Neural Repair

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