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Research article

First published 2010-2

Relevance of PK and PKPD modelling in rare diseases

Oscar Della Pasqua, Mariagrazia Felisi

Pharmaceuticals Policy and Law

Free access

Research article

First published 2021-2

Review of the Technical,Toxicological,and PKPD Considerations for Conducting Inhalation Toxicity Studies on Biologic Pharmaceuticals—The Outcome of a Cross-Industry Working Group Survey

Alison Wolfreys, Jo Kilgour, Andrew D. Allen [...]

Toxicologic Pathology

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Research article

First published 2025-2

Assessment of the Workflow and Time to Antibiotic Dose Adjustment for Critically Ill Patients Starting Continuous Renal Replacement Therapy

Megan Fulbright, Robert Sbertoli, Christian M. Gill

Hospital Pharmacy

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Research article

First published 2019-10

Estimation of Fraction Dissolved After Intratracheal Delivery of a Potent Janus Kinase Inhibitor,iJAK-001,with Low Solubility in Rat and Sheep: Impact of Preclinical PKPD on Inhaled Human Dose Projection

Michael Caniga, Hongshi Yu, Hyun-Hee Lee [...]

Journal of Aerosol Medicine and Pulmonary Drug Delivery

Open access

Review article

First published 2019-11

Statistical Methods for Adjusting Estimates of Treatment Effectiveness for Patient Nonadherence in the Context of Time-to-Event Outcomes and Health Technology Assessment: A Systematic Review of Methodological Papers

Abualbishr Alshreef, Nicholas Latimer, Paul Tappenden [...]

Medical Decision Making

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Research article

First published 2013-1

Multilevel Model of Type 1 Diabetes Mellitus Patients for Model-Based Glucose Controllers

Winston Garcia-Gabin, Elling W. Jacobsen

Journal of Diabetes Science and Technology

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Research article

First published 2017-2

Pharmacokinetics and pharmacodynamics of oral mecamylamine – development of a nicotinic acetylcholine receptor antagonist cognitive challenge test using modelling and simulation

Ricardo Alvarez-Jimenez, Anne Catrien Baakman, Jasper Stevens [...]

Journal of Psychopharmacology

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Research article

First published 2025-5

Levetiracetam dosing in continuous renal replacement therapy: A systematic review and development of a novel pharmacokinetic model to optimise dosing in critically ill patients. Do recommended doses achieve therapeutic drug concentrations?

James Sweatman, Sarraa Al-Mahdi, Dagan O Lonsdale [...]

Journal of the Intensive Care Society

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Research article

First published 2013-5

Electrophysiological Characterization and Antiarrhythmic Efficacy of the Mixed Potassium Channel-Blocking Antiarrhythmic Agent AZ13395438 In Vitro and In Vivo

Ingemar Jacobson, Göran Duker, Malin Florentzson [...]

Journal of Cardiovascular Pharmacology and Therapeutics

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Research article

First published 2021-4

Target Validation Using PROTACs: Applying the Four Pillars Framework

Radosław P. Nowak, Lyn H. Jones

Journal of Biomolecular Screening

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