Sage Journals: Discover world-class research

Open access

Research article

First published 2017-10

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors

Hana Paculová, Juraj Kramara, Šárka Šimečková [...]

Tumor Biology

Free access

Research article

First published 2018-2

Cell Density Affects the Detection of Chk1 Target Engagement by the Selective Inhibitor V158411

Clara C. Geneste, Andrew J. Massey

Journal of Biomolecular Screening

Free access

Research article

First published 2006-10

Development of a Screening Assay for Surrogate Markers of Chk1 Inhibitor-Induced Cell Cycle Release

Christie P. Fanton, Michael W. Rowe, Edward J. Moler [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2007-09

A Robust,Target-Driven,Cell-Based Assay for Checkpoint Kinase 1 Inhibitors

Tsuyoshi Ishii, Hiroshi Sootome, Alastair J. King [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2024-01

Cisplatin and Procaterol Combination in Gastric Cancer? Targeting Checkpoint Kinase 1 for Cancer Drug Discovery and Repurposing by an Integrated Computational and Experimental Approach

Suchitha Giridhara Prema, Jaikanth Chandrasekaran, Saptami Kanekar [...]

OMICS: A Journal of Integrative Biology

Free access

Research article

First published 2021-7

Role of inhibiting Chk1-p53 pathway in hepatotoxicity caused by chronic arsenic exposure from coal-burning

Yuan Yang, Chunyan Liu, Tingting Xie [...]

Human & Experimental Toxicology

Open access

Research article

First published 2020-1

TLC388 Induces DNA Damage and G2 Phase Cell Cycle Arrest in Human Non-Small Cell Lung Cancer Cells

Kun-Ming Wu, Chih-Wen Chi, Jerry Cheng-Yen Lai [...]

Cancer Control

Open access

Research article

First published 2020

Exploiting DNA repair defects in triple negative breast cancer to improve cell killing

Kevin J. Lee, Elise Mann, Griffin Wright [...]

Therapeutic Advances in Medical Oncology

Open access

Review article

First published 2025

Tumor-agnostic therapy: a potential therapeutic approach for SMARCA4-deficient malignancies

Yang Liu, Zhi-Hui Liu, Qiong Zhang [...]

Therapeutic Advances in Medical Oncology

Open access

Research article

First published 2020

Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma

Xiaoyang Li, Dylan C. Dean, Gregory M. Cote [...]

Therapeutic Advances in Medical Oncology

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