Abstract
The syntheses of hexa and tetra-propargylated pyrido[4′,3′:4,5]thieno[2,3-d]-pyrido[4″’,3″’:4″,5″]thieno[2″,3″:4′,5′] pyrimido[1′,2′:4,5]pyrazino[1,2-a]pyrimidines, are described by the reaction of hepta-annulated heterocyclic systems with propargyl bromide. Multiple alkyne-azide click reaction of these alkyne cores established them as a scaffold for six and four functionalised 1,2,3-triazoles and attached biomolecules.
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