Abstract
After the publication of this article, the authors noticed that the images in the panel LFB staining in Figure 4b were incorrect. These images have now been replaced with the correct images. The change does not influence the quantified results or the conclusion of the paper. The authors apologize for any problems this may have caused.
Effect of HO-1 on inflammation and white matter injury. (a) The expression of Iba1-, glial fibrillary acidic protein (GFAP)-, and myeloperoxidase (MPO)-immunoreactive cells around the injury site on day 3 after collagenase-induced ICH; n = 8 mice/group. The bar graph shows quantification analysis. (b) Immunofluorescent and Luxol fast blue (LFB) staining showing the expression of degraded myelin basic protein (dMBP), amyloid precursor protein (APP), and normal myelin (LFB) in the perihematoma region on day 3 after ICH. Arrows indicate damaged myelin, damaged axons, and normal myelin. The bar graphs show quantification analysis. n = 8 mice/group. *p < 0.05, **p < 0.01 vs. vehicle group. Values are means ± SD. Scale bar = 50 µm. (c) Diagram showing regions of analysis (labeled by Iba1). Dotted line indicates the hematoma. The rectangular boxes indicate the areas from which the images in a and b were taken at the periphery of the hematoma. Scale bar = 50 µm.