Abstract
Cultures of normal human epithelial cells were exposed to methylmercury alone or in combination with organic or inorganic selenium. The resulting subcellular distribution of mercury accumulation was demonstrated cytochemically by the silver enhancement method. With this method, accumulation of mercury-selenide complexes is visualised at both the light microscope and electron microscope levels. Substantially more mercury complexes were found in cultures exposed to mercury and selenite than in cultures exposed to mercury and selenomethionine. All visualised mercury-complexes were localised in lysosome-like structures.
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