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1-10 of 1379 results for targeted degradation

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Select article: A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications

Free access

Research article

First published 2021-8

A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications

Peter Stacey, Hannah Lithgow, Xiao Lewell [...]

Journal of Biomolecular Screening

Select article: High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics

Open access

Research article

First published 2021-4

High-Throughput Quantitative Assay Technologies for Accelerating the Discovery and Optimization of Targeted Protein Degradation Therapeutics

Jeffrey R. Simard, Linda Lee, Ellen Vieux [...]

Journal of Biomolecular Screening

Select article: Targeted Protein Degradation: An Important Tool for Drug Discovery for “Undruggable” Tumor Transcription Factors

Open access

Review article

First published 2022

Targeted Protein Degradation: An Important Tool for Drug Discovery for “Undruggable” Tumor Transcription Factors

Mengyuan Dai, Sridhar Radhakrishnan, Rui Li [...]

Technology in Cancer Research & Treatment

Select article: Facilitation of Responses to Degraded Targets by Non-Degraded Distractors

Retricted access

Research article

First published 2009-12

Facilitation of Responses to Degraded Targets by Non-Degraded Distractors

Brenda Ocampo, Ada Kritikos

Perception

Select article: Redox Modulation of Cellular Metabolism Through Targeted Degradation of Signaling Proteins by the Proteasome

Retricted access

Research article

First published 2006-01

Redox Modulation of Cellular Metabolism Through Targeted Degradation of Signaling Proteins by the Proteasome

Thomas C. Squier

Antioxidants & Redox Signaling

Select article: A Tale of Two Tails: Efficient Profiling of Protein Degraders by Specific Functional and Target Engagement Readouts

Open access

Research article

First published 2021-4

A Tale of Two Tails: Efficient Profiling of Protein Degraders by Specific Functional and Target Engagement Readouts

Alexey L. Chernobrovkin, Cindy Cázares-Körner, Tomas Friman [...]

Journal of Biomolecular Screening

Select article: Dual-Targeting Approach Degrades Biofilm Matrix and Enhances Bacterial Killing

Retricted access

Research article

First published 2019-3

Dual-Targeting Approach Degrades Biofilm Matrix and Enhances Bacterial Killing

Z. Ren, D. Kim, A.J. Paula [...]

Journal of Dental Research

Select article: Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis

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Research article

First published 2026-4

Targeting CCNB1 Repressed Cartilage Degradation Induced by Inflammation Through NF-κB Pathway in Osteoarthritis

Hua Li, Yuxue Qiao, Mengshuang Ding [...]

Journal of Histochemistry & Cytochemistry

Select article: Empowering Discovery in Targeted Protein Degradation

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Other

First published 2025-3

Empowering Discovery in Targeted Protein Degradation

Genetic Engineering & Biotechnology News

Select article: LncRNA MEG3 Inhibits the Degradation of the Extracellular Matrix of Chondrocytes in Osteoarthritis via Targeting miR-93/TGFBR2 Axis

Free access

Research article

First published 2021-12

LncRNA MEG3 Inhibits the Degradation of the Extracellular Matrix of Chondrocytes in Osteoarthritis via Targeting miR-93/TGFBR2 Axis

Kang Chen, Hao Zhu, Min-Qian Zheng [...]

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