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Research article

First published 2016-10

Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens

Rajarshi Guha, Lesley A. Mathews Griner, Jonathan M. Keller [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2010-2

Synthetic Lethality Induced by Loss of PKC δ and Mutated Ras

Tongbo Zhu, Lihua Chen, Wei Du [...]

Genes & Cancer

Open access

Review article

First published 2025

Targeting synthetic lethality: an effective therapeutic approach in ovarian and endometrial cancers

Alizée Lebeau, Athanasios Kakkos, Natacha Leroi [...]

Therapeutic Advances in Medical Oncology

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Research article

First published 2019-6

Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality

Dedrick Soon Seng Song, Sze Wei Leong, Kwok Wen Ng [...]

Journal of Biomolecular Screening

Open access

Research article

First published 2014

In Silico Prediction of Synthetic Lethality by Meta-Analysis of Genetic Interactions,Functions,and Pathways in Yeast and Human Cancer

Min Wu, Xuejuan Li, Fan Zhang [...]

Cancer Informatics

Retricted access

Research article

First published 2019-08

VHL Synthetic Lethality Signatures Uncovered by Genotype-Specific CRISPR-Cas9 Screens

Ning Sun, Sakina Petiwala, Charles Lu [...]

The CRISPR Journal

Retricted access

Research article

First published 2012-09

Leveraging Synthetic Lethality for Cancer

Patricia F. Dimond,

Genetic Engineering & Biotechnology News

Free access

Research article

First published 2015-12

A Comparison of Real-Time and Endpoint Cell Viability Assays for Improved Synthetic Lethal Drug Validation

Andrew Single, Henry Beetham, Bryony J. Telford [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2018-09

A Synthetic Micro-Consensus DNA Vaccine Generates Comprehensive Influenza A H3N2 Immunity and Protects Mice Against Lethal Challenge by Multiple H3N2 Viruses

Sarah T.C. Elliott, Amelia A. Keaton, Jacqueline D. Chu [...]

Human Gene Therapy

Free access

Research article

First published 2016-12

Anticancer Opportunity Created by Loss of Tumor Suppressor Genes

Xue Hui-Ying, Zhang Da-Hong, Ji Li-Juan [...]

Technology in Cancer Research & Treatment

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