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Research article

First published 2021-2

Core Hairpin Structure of SpCas9 sgRNA Functions in a Sequence- and Spatial Conformation–Dependent Manner

Mingjun Jiang, Yanzhen Ye, Juan Li

Journal of Laboratory Automation

Retricted access

Research article

First published 2025-11

RNAS-sgRNA: Recurrent Neural Architecture Search for Detection of On-Target Effects in Single Guide RNA

Shehla Rafiq, Assif Assad

Journal of Computational Biology

Retricted access

Research article

First published 2026

Computational Optimization of CRISPR-Cas13a sgRNAs Targeting the SARS-CoV-2 Spike Gene for SHERLOCK-Based Diagnostics

Maryam Ahmadzadeh, Fatemeh Akbarian, Mohammad Hossein Sanati [...]

Evolutionary Bioinformatics

Open access

Research article

First published 2024-12

Mass Spectrometry as a Quantitative Tool for SpCas9 sgRNA Quality Control

Juan Daniel Avila, Puzhou Wang

Nucleic Acid Therapeutics

Retricted access

Research article

First published 2022-09

An Optimized CRISPR/Cas9 Adenovirus Vector (AdZ-CRISPR) for High-Throughput Cloning of sgRNA,Using Enhanced sgRNA and Cas9 Variants

Evelina Statkute, Eddie C.Y. Wang, Richard J. Stanton

Human Gene Therapy

Open access

Research article

First published 2023-02

Miniature CRISPR-Cas12f1-Mediated Single-Nucleotide Microbial Genome Editing Using 3′-Truncated sgRNA

Ho Joung Lee, Hyun Ju Kim, Sang Jun Lee

The CRISPR Journal

Retricted access

Research article

First published 2025-06

Optimizing Genome Editing in Mollusks ( Crassostrea gigas ) in Vitro Validation of sgRNA and Identifying Key Factors Influencing Efficiency

Qian Li, Hong Yu, Shaojun Du [...]

The CRISPR Journal

Retricted access

Research article

First published 2021-04

Dead Cas9–sgRNA Complex Shelters Vulnerable DNA Restriction Enzyme Sites from Cleavage for Cloning Applications

Maryam Saifaldeen, Dana E. Al-Ansari, Dindial Ramotar [...]

The CRISPR Journal

Open access

Research article

First published 2025-02

Efficient Generation of SOCS2 Knock-Out Sheep by Electroporation of CRISPR-Cas9 Ribonucleoprotein Complex with Dual-sgRNAs

Ahmed K. Mahdi, Devon S. Fitzpatrick, Darren E. Hagen [...]

The CRISPR Journal

Free access

Research article

First published 2017-2

Efficient Management of High-Throughput Screening Libraries with SAVANAH

Markus List, Marlene Pedersen Elnegaard, Steffen Schmidt [...]

Journal of Biomolecular Screening

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