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Review article

First published 2025-1

Daprodustat: A Hypoxia-Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia of Chronic Kidney Disease

Haley N. Johnson, Lalita Prasad-Reddy

Annals of Pharmacotherapy

Free access

Research article

First published 2020-2

Carcinogenicity Assessment of Daprodustat (GSK1278863),a Hypoxia-Inducible Factor (HIF)-Prolyl Hydroxylase Inhibitor

David F. Adams, Mark S. Watkins, Luc Durette [...]

Toxicologic Pathology

Open access

Research article

First published 2023-1

Assessing the Carcinogenicity of Vadadustat,an Oral Hypoxia-Inducible Factor Prolyl-4-Hydroxylase Inhibitor,in Rodents

Heather Kowalski, Debie Hoivik, Michael Rabinowitz

Toxicologic Pathology

Free access

Research article

First published 2017-11

Evaluation of the Carcinogenic Potential of Roxadustat (FG-4592),a Small Molecule Inhibitor of Hypoxia-Inducible Factor Prolyl Hydroxylase in CD-1 Mice and Sprague Dawley Rats

James Beck, Carroll Henschel, James Chou [...]

International Journal of Toxicology

Free access

Research article

First published 2023-12

Evaluation of the Carcinogenic Potential of Enarodustat (JTZ-951),a Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor,in 26-Week Tg.rasH2 Mouse Study and 2-Year Sprague-Dawley Rat Study

Yusuke Kemmochi, Kaoru Toyoda, Tomio Ishida [...]

International Journal of Toxicology

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Research article

First published 2025

Application of Vadadustat in chronic kidney disease

Jia Cao

Journal of Computational Methods in Sciences and Engineering

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Research article

First published 2026-4

Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitor Roxadustat Accelerates Wound Healing in a Mouse Hind limb Lymphedema Model

Kosuke Ishikawa, Yoshitada Hoshino, Masayuki Osawa [...]

Advances in Wound Care

Open access

Editorial

First published 2010-02

Prolyl Hydroxylases and Therapeutics

Thomas G. Smith, Nick P. Talbot

Antioxidants & Redox Signaling

Open access

Case report

First published 2021-4

Successful application of roxadustat in the treatment of patients with anti-erythropoietin antibody-mediated renal anaemia: a case report and literature review

Ke-Dan Cai, Bei-Xia Zhu, Hai-Xue Lin [...]

Journal of International Medical Research

Open access

Research article

First published 2017-5

Ginsenoside 20(S)-Rg3 suppresses ovarian cancer migration via hypoxia-inducible factor 1 alpha and nuclear factor-kappa B signals

Ting Liu, Le Zhao, Huilian Hou [...]

Tumor Biology

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