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Articles (85)

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1-10 of 85 results for early drug-discovery stage

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Select article: The BlueScreen-384 Assay as an Indicator of Genotoxic Hazard Potential in Early-Stage Drug Discovery

Free access

Research article

First published 2013-4

The BlueScreen-384 Assay as an Indicator of Genotoxic Hazard Potential in Early-Stage Drug Discovery

Kate Simpson, Nicola Bevan, Paul Hastwell [...]

Journal of Biomolecular Screening

Select article: Rochester v. Searle: Complying with the Written Description and Enablement Requirements in Early-Stage Drug Discovery

Retricted access

Research article

First published 2003-10

Rochester v. Searle: Complying with the Written Description and Enablement Requirements in Early-Stage Drug Discovery

Anne Y. Brody

Biotechnology Law Report

Select article: “Pulling the Plug:” Time Allocation between Drug Discovery and Development Projects

Retricted access

Research article

First published 2020-12

“Pulling the Plug:” Time Allocation between Drug Discovery and Development Projects

Annapoornima M. Subramanian, Moren Lévesque, Vareska van de Vrande

Production and Operations Management

Select article: A System for LogD Screening of New Drug Candidates using a Water-Plug Injection Method and Automated Liquid Handler

Free access

Other

First published 2009-4

A System for LogD Screening of New Drug Candidates using a Water-Plug Injection Method and Automated Liquid Handler

Taro Yamashita, Ikuko Nishimura, Tatsuji Nakamura [...]

Journal of Laboratory Automation

Select article: Recommended Guidelines for Developing,Qualifying,and Implementing Complex In Vitro Models (CIVMs) for Drug Discovery

Free access

Research article

First published 2020-12

Recommended Guidelines for Developing,Qualifying,and Implementing Complex In Vitro Models (CIVMs) for Drug Discovery

Jason E. Ekert, Julianna Deakyne, Philippa Pribul-Allen [...]

Journal of Biomolecular Screening

Select article: A Novel In Vitro Approach for Simultaneous Evaluation of CYP3A4 Inhibition and Kinetic Aqueous Solubility

Free access

Research article

First published 2015-2

A Novel In Vitro Approach for Simultaneous Evaluation of CYP3A4 Inhibition and Kinetic Aqueous Solubility

José Pérez, Caridad Díaz, Francisco Asensio [...]

Journal of Biomolecular Screening

Select article: Automated Luminescence-Based Cytochrome P450 Profiling Using a Simple,Elegant Robotic Platform

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Other

First published 2011-2

Automated Luminescence-Based Cytochrome P450 Profiling Using a Simple,Elegant Robotic Platform

Brad Larson, Peter Banks, James J. Cali [...]

Journal of Laboratory Automation

Select article: 3D Cell-Based Assays for Drug Screens: Challenges in Imaging,Image Analysis,and High-Content Analysis

Open access

Review article

First published 2019-7

3D Cell-Based Assays for Drug Screens: Challenges in Imaging,Image Analysis,and High-Content Analysis

Tijmen H. Booij, Leo S. Price, Erik H. J. Danen

Journal of Biomolecular Screening

Select article: Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

Open access

Research article

First published 2019-2

Positioning High-Throughput CETSA in Early Drug Discovery through Screening against B-Raf and PARP1

Joseph Shaw, Ian Dale, Paul Hemsley [...]

Journal of Biomolecular Screening

Select article: How to Assess Simple Screening Strategies

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Other

First published 2001-4

How to Assess Simple Screening Strategies

Dhammika Amaratunga

Therapeutic Innovation & Regulatory Science

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