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Research article

First published 2020-3

Predictivity/Translatability of Toxicities Observed in Nonclinical Toxicology Studies to Clinical Safety Outcomes in Drug Development: Case Examples

Nicola J. Stagg, Hanan N. Ghantous, Robert Roth [...]

International Journal of Toxicology

Retricted access

Research article

First published 1990-11

The Safety Evaluation of Drugs and Chemicals by the Use of Computer Optimised Molecular Parametric Analysis of Chemical Toxicity (COMPACT)

Dennis V. Parke, Costas Ioannides, David F.V. Lewis

Alternatives to Laboratory Animals

Retricted access

Research article

First published 2015-12

Predicting Human Drug Toxicity and Safety via Animal Tests: Can Any One Species Predict Drug Toxicity in Any Other,and Do Monkeys Help?

Jarrod Bailey, Michelle Thew, Michael Balls

Alternatives to Laboratory Animals

Open access

Research article

First published 2021-03

Combination of Hydroxychloroquine Plus Azithromycin As Potential Treatment for COVID-19 Patients: Safety Profile,Drug Interactions,and Management of Toxicity

Guillaume Hache, Jean Marc Rolain, Philippe Gautret [...]

Microbial Drug Resistance

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Research article

First published 2022-12

The Dog as a Second Species for Toxicology Testing Provides Value to Drug Development

Nancy Bower, William E. Achanzar, Virginie Boulifard [...]

International Journal of Toxicology

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Meeting report

First published 1966-11

Some Aspects of Toxicity Testing in the Safety Assessment of a Drug

T. L. Hardy

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

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Research article

First published 2019-2

Toxicologic Pathology Forum: Current Status on the Use of Animal Models of Human Disease in the Pharmaceutical Industry in Japan in Nonclinical Safety Assessment–Opinion Paper

Masayuki Tomohiro, Takeshi Okabe, Yasushi Kimura [...]

Toxicologic Pathology

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Review article

First published 2010-8

Inbred Strains Should Replace Outbred Stocks in Toxicology,Safety Testing,and Drug Development

Michael F. W. Festing

Toxicologic Pathology

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Review article

First published 2024-10

Weight of Evidence: Is an Animal Study Warranted? Assessments for Carcinogenicity,Drug Abuse Liability,and Pediatric Safety

Thulasi Ramani, Ronald L. Wange, T. Scott Manetz [...]

International Journal of Toxicology

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Book review

First published 2012-7

Book Review: Histopathology of Preclinical Toxicity Studies,Fourth Edition: Interpretation and Relevance in Drug Safety Evaluation

J. M. Ward

Veterinary Pathology

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