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Articles (55)

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1-10 of 55 results for biomarker-stratified trials

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Select article: Isotonic design for single-arm biomarker stratified trials

Open access

Research article

First published 2024-6

Isotonic design for single-arm biomarker stratified trials

Lang Li, Anastasia Ivanova

Statistical Methods in Medical Research

Select article: A Bayesian adaptive biomarker stratified phase II randomized clinical trial design for radiotherapies with competing risk survival outcomes

Free access

Research article

First published 2024-1

A Bayesian adaptive biomarker stratified phase II randomized clinical trial design for radiotherapies with competing risk survival outcomes

Jina Park, Wenjing Hu, Ick Hoon Jin [...]

Statistical Methods in Medical Research

Select article: Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

Open access

Research article

First published 2022-4

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

Louise C Brown, Janet Graham, David Fisher [...]

Clinical Trials

Select article: Bias in retrospective analyses of biomarker effect using data from an outcome-adaptive randomized trial

Retricted access

Research article

First published 2019-12

Bias in retrospective analyses of biomarker effect using data from an outcome-adaptive randomized trial

Lingyun Ji, Lisa M McShane, Mark Krailo [...]

Clinical Trials

Select article: Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

Free access

Other

First published 2015-7

Biomarkers for risk stratification of patients with ST-elevation myocardial infarction treated with primary percutaneous coronary intervention: insights from the PLATelet inhibition and patient Outcomes (PLATO) trial

Gina Sanki

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine

Select article: Optimal two-stage enrichment design correcting for biomarker misclassification

Retricted access

Research article

First published 2018-1

Optimal two-stage enrichment design correcting for biomarker misclassification

Yong Zang, Beibei Guo

Statistical Methods in Medical Research

Select article: Integrating biomarker information within trials to evaluate treatment mechanisms and efficacy for personalised medicine

Open access

Research article

First published 2013-10

Integrating biomarker information within trials to evaluate treatment mechanisms and efficacy for personalised medicine

Graham Dunn, Richard Emsley, Hanhua Liu [...]

Clinical Trials

Select article: Improving Drug Trial Success Rates in Systemic Lupus Erythematosus: Endotyping-based Patient Stratification Could be the way Forward

Open access

Research article

First published 2024-3

Improving Drug Trial Success Rates in Systemic Lupus Erythematosus: Endotyping-based Patient Stratification Could be the way Forward

Anand N. Malaviya, Neeraj Jain

Indian Journal of Rheumatology

Select article: PD-L1/PD-1 Biomarker for Metastatic Urothelial Cancer that Progress Post-platinum Therapy: A Systematic Review and Meta-analysis

Open access

Review article

First published 2019

PD-L1/PD-1 Biomarker for Metastatic Urothelial Cancer that Progress Post-platinum Therapy: A Systematic Review and Meta-analysis

Wei Phin Tan, Wei Shen Tan, Brant A. Inman

Bladder Cancer

Select article: Development of Breast Cancer Therapy: Biomarker-Driven and Response-Guided Approaches in a Neoadjuvant Setting

Free access

Letter

First published 2015

Development of Breast Cancer Therapy: Biomarker-Driven and Response-Guided Approaches in a Neoadjuvant Setting

Masakazu Toi, Norikazu Masuda, Hiroshi Ishiguro [...]

The International Journal of Biological Markers

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