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Articles (52)

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1-10 of 52 results for biomarker stratified design

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Select article: Isotonic design for single-arm biomarker stratified trials

Open access

Research article

First published 2024-6

Isotonic design for single-arm biomarker stratified trials

Lang Li, Anastasia Ivanova

Statistical Methods in Medical Research

Select article: A Bayesian adaptive biomarker stratified phase II randomized clinical trial design for radiotherapies with competing risk survival outcomes

Free access

Research article

First published 2024-1

A Bayesian adaptive biomarker stratified phase II randomized clinical trial design for radiotherapies with competing risk survival outcomes

Jina Park, Wenjing Hu, Ick Hoon Jin [...]

Statistical Methods in Medical Research

Select article: Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

Open access

Research article

First published 2022-4

Experiences of running a stratified medicine adaptive platform trial: Challenges and lessons learned from 10 years of the FOCUS4 trial in metastatic colorectal cancer

Louise C Brown, Janet Graham, David Fisher [...]

Clinical Trials

Select article: Bias in retrospective analyses of biomarker effect using data from an outcome-adaptive randomized trial

Retricted access

Research article

First published 2019-12

Bias in retrospective analyses of biomarker effect using data from an outcome-adaptive randomized trial

Lingyun Ji, Lisa M McShane, Mark Krailo [...]

Clinical Trials

Select article: Optimal two-stage enrichment design correcting for biomarker misclassification

Retricted access

Research article

First published 2018-1

Optimal two-stage enrichment design correcting for biomarker misclassification

Yong Zang, Beibei Guo

Statistical Methods in Medical Research

Select article: Integrating biomarker information within trials to evaluate treatment mechanisms and efficacy for personalised medicine

Open access

Research article

First published 2013-10

Integrating biomarker information within trials to evaluate treatment mechanisms and efficacy for personalised medicine

Graham Dunn, Richard Emsley, Hanhua Liu [...]

Clinical Trials

Select article: Lung Adenocarcinoma Systems Biomarker and Drug Candidates Identified by Machine Learning,Gene Expression Data,and Integrative Bioinformatics Pipeline

Retricted access

Research article

First published 2024-08

Lung Adenocarcinoma Systems Biomarker and Drug Candidates Identified by Machine Learning,Gene Expression Data,and Integrative Bioinformatics Pipeline

Semra Melis Soyer, Pemra Ozbek, Ceyda Kasavi

OMICS: A Journal of Integrative Biology

Select article: Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease

Open access

Research article

First published 2020-11

Night Watch on the Titanic: Detecting Early Signs of Epileptogenesis in Alzheimer Disease

Alice D. Lam, Jeffrey Noebels

Epilepsy Currents

Select article: Staging and Personalized Intervention for Infection and Sepsis

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Review article

First published 2020-11

Staging and Personalized Intervention for Infection and Sepsis

Nadine Beckmann, Christen E. Salyer, Peter A. Crisologo [...]

Surgical Infections

Select article: Performance of plasminogen activator inhibitor-1 as a biomarker in patients undergoing coronary angiography: Analytical and biological considerations

Free access

Brief report

First published 2019-9

Performance of plasminogen activator inhibitor-1 as a biomarker in patients undergoing coronary angiography: Analytical and biological considerations

Richard G Jung, Trevor Simard, Pietro Di Santo [...]

Diabetes & Vascular Disease Research

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