Sage Journals: Discover world-class research

Open access

Research article

First published 2022-3

Discovery of an SphK1 inhibitor: A hybrid approach involving a receptor–ligand-complex-based pharmacophore and docking-based virtual screening

Tiandi Ding, HaiJiao Chen, Yan Li [...]

Journal of Chemical Research

Open access

Review article

First published 2020-10

The Tumorigenic Effect of Sphingosine Kinase 1 and Its Potential Therapeutic Target

Xianwang Wang, Yong Sun, Xiaochun Peng [...]

Cancer Control

Open access

Research article

First published 2021

The role of the sphingosine axis in immune regulation: A dichotomy in the anti-inflammatory effects between sphingosine kinase 1 and sphingosine kinase 2-dependent pathways

Yuval Ishay, Dvorah Rotnemer-Golinkin, Yaron Ilan

International Journal of Immunopathology and Pharmacology

Open access

Research article

First published 2021-7

L-ascorbyl 6-palmitate as lead compound targeting SphK1: an in silico and in vitro investigation

HaiJiao Chen, Xinmei Yang, Peng Sun [...]

Journal of Chemical Research

Open access

Research article

First published 2023-02

The impacts of SphK1 on inflammatory response and oxidative stress in LPS-induced ALI/ARDS

Wei Chao-shun, Wang Xiao-Li

European Journal of Inflammation

Retricted access

Research article

First published 2016-02

A High-Throughput Genetic Complementation Assay in Yeast Cells Identified Selective Inhibitors of Sphingosine Kinase 1 Not Found Using a Cell-Free Enzyme Assay

Mohammed A. Kashem, Charles A. Kennedy, Kylie E. Fogarty [...]

ASSAY and Drug Development Technologies

Retricted access

Research article

First published 2015-11

Activation of SphK1 by K6PC-5 Inhibits Oxygen–Glucose Deprivation/Reoxygenation-Induced Myocardial Cell Death

Jun-jie Shao, Yi Peng, Li-ming Wang [...]

DNA and Cell Biology

Retricted access

Research article

First published 2023-1

Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes

Gulibositan Aji, Sheng Jiang, Halmurat Obulkasim [...]

Experimental Biology and Medicine

Free access

Research article

First published 2016-9

Sphingosine-1-Phosphate is Involved in the Occlusive Arteriopathy of Pulmonary Arterial Hypertension

Salina Gairhe, Sachindra R. Joshi, Mrigendra M. Bastola [...]

Pulmonary Circulation

Retricted access

Research article

First published 2018-11

Ginsenoside Rb1 Enhances Keratinocyte Migration by a Sphingosine-1-Phosphate-Dependent Mechanism

Kyong-Oh Shin, Sung Jay Choe, Yoshikazu Uchida [...]

Journal of Medicinal Food

Search results