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Articles (9)

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1-9 of 9 results for IRAK4

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Select article: Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery

Free access

Research article

First published 2021-9

Establishing and Validating Cellular Functional Target Engagement Assay for Selective IRAK4 Inhibitor Discovery

Yiping Chen, Dongyu Sun, Ruojing Yang [...]

Journal of Biomolecular Screening

Select article: GPx3 Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglial Pyroptosis Through IRAK4/ROS/NLRP3 Axis

Retricted access

Research article

First published 2025-05

GPx3 Promotes Functional Recovery after Spinal Cord Injury by Inhibiting Microglial Pyroptosis Through IRAK4/ROS/NLRP3 Axis

Zhongyuan Liu, Jiawei Shi, Kewu Tu [...]

Antioxidants & Redox Signaling

Select article: A Kinome-Wide siRNA Screen Identifies Multiple Roles for Protein Kinases in Hypoxic Stress Adaptation,Including Roles for IRAK4 and GAK in Protection against Apoptosis in VHL −/− Renal Carcinoma Cells,Despite Activation of the NF-κB Pathway

Free access

Research article

First published 2013-8

A Kinome-Wide siRNA Screen Identifies Multiple Roles for Protein Kinases in Hypoxic Stress Adaptation,Including Roles for IRAK4 and GAK in Protection against Apoptosis in VHL −/− Renal Carcinoma Cells,Despite Activation of the NF-κB Pathway

Jing Pan, Jing Zhang, Andrew Hill [...]

Journal of Biomolecular Screening

Select article: Heritable defects of the human TLR signalling pathways

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Other

First published 2005-08

Heritable defects of the human TLR signalling pathways

Anne Puel, Kun Yang, Cheng-Lung Ku [...]

Innate Immunity

Select article: Mouse pyrin and HIN domain family member 1 (pyhin1) protein positively regulates LPS-induced IFN-β and NO production in macrophages

Free access

Research article

First published 2014-2

Mouse pyrin and HIN domain family member 1 (pyhin1) protein positively regulates LPS-induced IFN-β and NO production in macrophages

Abedul Haque, Naoki Koide, Erdenezaya Odkhuu [...]

Innate Immunity

Select article: TLR4 overexpression enhances saturated fatty acid–induced inflammatory cytokine gene expression in sheep

Open access

Letter

First published 2018

TLR4 overexpression enhances saturated fatty acid–induced inflammatory cytokine gene expression in sheep

Xue Xu, Mei-Yu Qi, Shuang Liu [...]

European Journal of Inflammation

Select article: Lps2: a new locus required for responses to lipopolysaccharide,revealed by germline mutagenesis and phenotypic screening

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Research article

First published 2003-08

Lps2: a new locus required for responses to lipopolysaccharide,revealed by germline mutagenesis and phenotypic screening

Kasper Hoebe, Xin Du, Jason Goode [...]

Innate Immunity

Select article: A Three-Dimensional Lymphatic Endothelial Cell Tube Formation Assay to Identify Novel Kinases Involved in Lymphatic Vessel Remodeling

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Research article

First published 2017-01

A Three-Dimensional Lymphatic Endothelial Cell Tube Formation Assay to Identify Novel Kinases Involved in Lymphatic Vessel Remodeling

T. Jessica Gambino, Steven P. Williams, Carol Caesar [...]

ASSAY and Drug Development Technologies

Select article: Distinct post-receptor alterations generate gene- and signal-selective adaptation and cross-adaptation of TLR4 and TLR2 in human leukocytes

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Other

First published 2003-02

Distinct post-receptor alterations generate gene- and signal-selective adaptation and cross-adaptation of TLR4 and TLR2 in human leukocytes

Liwu Li, Randy Jacinto, Barbara Yoza [...]

Innate Immunity

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