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Open access

Review article

First published 2022-5

Exploring the Definition of “Similar Toxicities”: Case Studies Illustrating Industry and Regulatory Interpretation of ICH S6(R1) for Long-Term Toxicity Studies in One or Two Species

Helen Prior, David O Clarke, David Jones [...]

International Journal of Toxicology

Open access

Research article

First published 2021-04

Considerations of the Japanese Research Working Group for the ICH S6 & Related Issues Regarding Nonclinical Safety Assessments of Oligonucleotide Therapeutics: Comparison with Those of Biopharmaceuticals

Yoko Hirabayashi, Kazushige Maki, Kiyoshi Kinoshita [...]

Nucleic Acid Therapeutics

Free access

Research article

First published 2013-12

Society of Toxicologic Pathology Position Paper on Best Practices on Recovery Studies

Rick Perry, Georgia Farris, Jean-Guy Bienvenu [...]

Toxicologic Pathology

Free access

Research article

First published 2022-6

Safety Assessment of 1-Hydroxyethyl 4,5-Diamino Pyrazole Sulfate as Used in Cosmetics

Christina L. Burnett, Wilma F. Bergfeld, Donald V. Belsito [...]

International Journal of Toxicology

Free access

Research article

First published 2008-7

Nonclinical Aspects of Biopharmaceutical Development: Discussion of Case Studies at a PhRMA-FDA Workshop

L. A. Buckley, K. Benson, K. Davis-Bruno [...]

International Journal of Toxicology

Free access

Review article

First published 2023-12

Alternatives to Monkey Reproductive Toxicology Testing for Biotherapeutics

Alan M. Hoberman, Kazushige Maki, Fumito Mikashima [...]

International Journal of Toxicology

Open access

Review article

First published 2024-10

Exploring Greater Flexibility for Chronic Toxicity Study Designs to Support Human Safety Assessment While Balancing 3Rs Considerations

Helen Prior, Paul Baldrick, David O. Clarke [...]

International Journal of Toxicology

Retricted access

Research article

First published 2022-2

Acupuncture inhibits mammalian target of rapamycin,promotes autophagy and attenuates neurological deficits in a rat model of hemorrhagic stroke

Hao Liu, Beng Zhang, Xin-Wei Li [...]

Acupuncture in Medicine

Free access

Meeting report

First published 2021-3

Development and Regulatory Challenges for Peptide Therapeutics

Doris Zane, Paul L. Feldman, Tomi Sawyer [...]

International Journal of Toxicology

Free access

Review article

First published 2018-10

A Brief Introduction to Antibody–Drug Conjugates for Toxicologic Pathologists

Lars Mecklenburg

Toxicologic Pathology

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