Sage Journals: Discover world-class research

Free access

Research article

First published 2017-7

Clenbuterol Attenuates hERG Channel by Promoting the Mature Channel Degradation

Ling Luo, Peijing Hu, Changqing Miao [...]

International Journal of Toxicology

Free access

Research article

First published 2006-1

Utility of hERG Assays as Surrogate Markers of Delayed Cardiac Repolarization and QT Safety

Gary A. Gintant, Zhi Su, Ruth L. Martin [...]

Toxicologic Pathology

Free access

Research article

First published 2005-06

Evaluation of a High-Throughput Fluorescence Assay Method for hERG Potassium Channel Inhibition

Arnulf Dorn, Francis Hermann, Andreas Ebneth [...]

Journal of Biomolecular Screening

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Other

First published 2005-8

Assessing hERG Channel Inhibition Using PatchXpress

Justin Q. Ly, Gordon Shyy, Dinah L. Misner

Journal of Laboratory Automation

Free access

Research article

First published 2011-10

In Silico–Based Structural Analysis of Arylthiophene Derivatives for FTase Inhibitory Activity,hERG,and Other Toxic Effects

N. S. Hari Narayana Moorthy, Sergio F. Sousa, Maria J. Ramos [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2014-7

Roles of PKC Isoforms in PMA-Induced Modulation of the hERG Channel (Kv11.1)

Olivier Radresa, António Guia, Ghayath Baroudi

Journal of Biomolecular Screening

Free access

Research article

First published 2005-12

A Place for High-Throughput Electrophysiology in Cardiac Safety: Screening hERG Cell Lines and Novel Compounds with the Ion Works HTTM System

Heather Guthrie, Frederick S. Livingston, Ueli Gubler [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2004-10

Rb+ Flux through hERG Channels Affects the Potency of Channel Blocking Drugs: Correlation with Data Obtained Using a High-Throughput Rb+ Efflux Assay

Saman Rezazadeh, J. Christian Hesketh, David Fedida

Journal of Biomolecular Screening

Open access

Research article

First published 2023-04

Time Is a Critical Factor When Evaluating Oligonucleotide Therapeutics in hERG Assays

Yusheng Qu, Robert Kirby, Richard Davies [...]

Nucleic Acid Therapeutics

Retricted access

Research article

First published 2008-04

Improved Throughput of PatchXpress hERG Assay Using Intracellular Potassium Fluoride

Haoyu Zeng, Jacob R. Penniman, Fumi Kinose [...]

ASSAY and Drug Development Technologies

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