Sage Journals: Discover world-class research

Open access

Research article

First published 2017-10

BRCA1 or CDK12 loss sensitizes cells to CHK1 inhibitors

Hana Paculová, Juraj Kramara, Šárka Šimečková [...]

Tumor Biology

Free access

Research article

First published 2006-10

Development of a Screening Assay for Surrogate Markers of Chk1 Inhibitor-Induced Cell Cycle Release

Christie P. Fanton, Michael W. Rowe, Edward J. Moler [...]

Journal of Biomolecular Screening

Retricted access

Research article

First published 2026-2

Phosphoregulation for Therapeutic Interventions in Cancer? Phosphoregulatory Map of Checkpoint Kinase 1 (CHK1) Uncovers Unexplored Regulatory Layers

Mejo George, Leona Dcunha, Levin John [...]

OMICS: A Journal of Integrative Biology

Free access

Research article

First published 2018-2

Cell Density Affects the Detection of Chk1 Target Engagement by the Selective Inhibitor V158411

Clara C. Geneste, Andrew J. Massey

Journal of Biomolecular Screening

Free access

Research article

First published 2022-2

Plasma checkpoint protein 1 (Chk1) as a potential diagnostic biomarker for opisthorchiasis and cholangiocarcinoma

Teva Phanaksri, Yodying Yingchutrakul, Sittiruk Roytrakul [...]

Cancer Biomarkers

Free access

Research article

First published 2006-10

Kinase Drug Discovery by Affinity Selection/Mass Spectrometry (ASMS): Application to DNA Damage Checkpoint Kinase Chk1

Kenneth M. Comess, Jonathan D. Trumbull, Chang Park [...]

Journal of Biomolecular Screening

Free access

Research article

First published 2021-7

Role of inhibiting Chk1-p53 pathway in hepatotoxicity caused by chronic arsenic exposure from coal-burning

Yuan Yang, Chunyan Liu, Tingting Xie [...]

Human & Experimental Toxicology

Open access

Research article

First published 2020

Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma

Xiaoyang Li, Dylan C. Dean, Gregory M. Cote [...]

Therapeutic Advances in Medical Oncology

Open access

Research article

First published 2024-12

Enhancing the Efficacy of Radiotherapy in Gastric Adenocarcinoma Cells by Gut Microbiota Metabolites: Implications for Urolithin Combination Therapy

Abdolreza Ahmadi, Fatemehsadat Hosseini, Hassan Ostadi [...]

Natural Product Communications

Free access

Research article

First published 2007-09

A Robust,Target-Driven,Cell-Based Assay for Checkpoint Kinase 1 Inhibitors

Tsuyoshi Ishii, Hiroshi Sootome, Alastair J. King [...]

Journal of Biomolecular Screening

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