Sage Journals: Discover world-class research

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Research article

First published 2017-04

A Conjugate of Two tPA-Binding RNA Aptamers Efficiently Inhibits Fibrinolysis

Nils Bjerregaard, Daniel M. Dupont, Peter A. Andreasen

Nucleic Acid Therapeutics

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Research article

First published 2025-10

Binding and Ligand Activation Driven Enrichment–Directed Evolution of SaCas9 gRNAs Improves Gene Editing Efficiency

Telmo Llanga, Korie Bush, Ying Sun [...]

Nucleic Acid Therapeutics

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Research article

First published 2016-4

An Efficient and Economical Assay to Screen for Triclosan Binding to FabI

Robel D. Demissie, Pauline Kabre, Micheal L. Tuntland [...]

Journal of Biomolecular Screening

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Research article

First published 2016-05

comets (Constrained Optimization of Multistate Energies by Tree Search): A Provable and Efficient Protein Design Algorithm to Optimize Binding Affinity and Specificity with Respect to Sequence

Mark A. Hallen, Bruce R. Donald

Journal of Computational Biology

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Research article

First published 2016-10

Application of an industrial waste magnetic iron dust as a solid phase support for immobilizing enzyme of industrial applications

Jagdish Shantilal Patel, Darshan H Patel, Rucha Desai [...]

Adsorption Science & Technology

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Research article

First published 2018-07

BBK* (Branch and Bound Over K*): A Provable and Efficient Ensemble-Based Protein Design Algorithm to Optimize Stability and Binding Affinity Over Large Sequence Spaces

Adegoke A. Ojewole, Jonathan D. Jou, Vance G. Fowler [...]

Journal of Computational Biology

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Research article

First published 2014-03

Replacement of the V3 Domain in the Surface Subunit of the Feline Immunodeficiency Virus Envelope Glycoprotein with the Equivalent Region of a T Cell-Tropic Human Immunodeficiency Virus Type 1 Results in a Chimeric Surface Protein That Efficiently Binds to CXCR4

Silvia A. González, Juan I. Falcón, José L. Affranchino

AIDS Research and Human Retroviruses

Open access

Research article

First published 2022-5

Combining classical molecular docking with self-consistent charge density-functional tight-binding computations for the efficient and quality prediction of ligand binding structure

Amar Y Al-Ansi, Haorui Lu, Zijing Lin

Journal of Chemical Research

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Research article

First published 1990-06

Efficient Binding of Glucocorticoid Receptor to Its Responsive Element Requires a Dimer and DNA Flanking Sequences

Georges Chalepakis, Michael Schauer, Xinan Cao [...]

DNA and Cell Biology

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Research article

First published 2010-10

Identification of Selective Enzyme Inhibitors by Fragment Library Screening

Geng Gao, Xuying Liu, Alexander Pavlovsky [...]

Journal of Biomolecular Screening

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