Tumour lysis syndrome is rare in solid malignancies. Here, we report a case of tumour lysis syndrome and acute kidney injury in a 23-year-old female with gestational trophoblastic neoplasia. Hydration and early dialysis therapy were started with good recovery. On follow up she progressed to chronic kidney disease. After 6 years of follow up, the patient conceived and delivered successfully.
BellomoR, RoncoC, KellumJA. Acute renal failure -definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI) Group. Crit Care2004; 8: R204-12.
5.
MehtaRI, KellumJA, ShahSV. Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury. Crit Care2007; 11: R31.
SchumanS, PearsonJM, LucciJA. Metastatic gestational trophoblastic neoplasia complicated by tumor lysis syndrome, heart failure, and thyrotoxicosis: a case report. J Reprod Med2010; 55: 441–4.
8.
MirrakhimovAE, AliAM, KhanM. Tumor lysis syndrome in solid tumors: an up to date review of the literature. Rare Tumors2014; 6:5389.
9.
VodopivecDM, RubioJE, FornoniA. An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review. Case Rep Med2012; 2012:12.
10.
CoiffierB. Acute tumor lysis syndrome—a rare complication in the treatment of solid tumors. Onkologie2010; 33: 498–9.
11.
ShimadaM, JohnsonRJ, MayWSJr. A novel role for uric acid in acute kidney injury associated with tumour lysis syndrome. Nephrol Dial Transplant2009; 24: 2960–4.
12.
LoLJ, GoAS, ChertowGM. Dialysis-requiring acute renal failure increases the risk of progressive chronic kidney disease. Kidney Int2009; 76: 893–9.
13.
LiL, YangC, ZhaoY. Is hyperuricemia an independent risk factor for new-onset chronic kidney disease? A systematic review and meta-analysis based on observational cohort studies. BMC Nephrol2014; 15:122.
14.
PrakashJ, GanigerVC, PrakashS. Acute kidney injury in pregnancy with special reference to pregnancy-specific disorders: a hospital-based study (2014–2016). J Nephrol2018; 31: 79–85.
15.
SongHZ, WuPC, WangYE. Pregnancy outcomes after successful chemotherapy for choriocarcinoma and invasive mole: long-term follow-up. Am J Obstet Gynecol1988; 158: 538–45.
16.
GadducciA, LanfrediniN, CosioS. Reproductive outcomes after hydatiform mole and gestational trophoblastic neoplasia. Gynecol Endocrinol2015; 31: 673–8.
