Sir John Cornforth's work on the stereochemistry of enzyme reactions involved in the biosynthesis of squalene and cholesterol and in the formation and metabolism of a chiral methyl group in acetyl co-enzyme A, is reviewed.
RobinsonR. (1955) The structural relations of natural products.Oxford University Press.
2.
OgstonA.G. (1948) Nature (Lond.), 162, 963.
3.
CornforthJ.W. (1953) Endeavour, 12, 61–67.
4.
RuzickaL., and StollM. (1922) Helv. Chim Acta, 5, 923–930.
5.
RobinsonR. (1934) J. Soc. Chem. Ind., Lond., 58, 1062–1063.
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8.
LangdonR.G., and BlochK. (1952) J. Am. Chem. Soc., 74, 1869–1870.
9.
CornforthJ.W., HunterG.D., and PopjákG.J. (1953) Biochem. J., 54, 597–601.
10.
CornforthJ.W., HunterG.D., and PopjákG.J. (1953) Biochem. J., 54, 590–597.
11.
CornforthJ.W., GoreI.Y., and PopjákG.J. (1957) Biochem. J., 65, 94–109.
12.
CornforthJ.W., and PopjákG.J. (1954) Biochem. J., 58, 403–407.
13.
CornforthJ.W., YouhotskyI., and PopjákG.J. (1954) Nature (Lond.), 173, 536–538.
14.
TavorminaP.A., GibbsM.H., and HuffJ.W. (1956) J. Am. Chem. Soc., 78, 4498–4499.
15.
WolfD.E., HoffmanC.H., AldrichP.E., SkeggsH.R., WrightL.D., and FolkersK. (1956) J. Am. Chem. Soc., 78, 4499.
16.
CornforthJ.W., CornforthR.H., PopjákG.J., and GoreI. (1957) Biochem. J., 66, 10P.
17.
CornforthJ.W., CornforthR.H., PopjákG.J., and GoreI. (1958) Biochem. J., 69, 146–155.
18.
LynenF., EggererH., HenningU., and KesslerI. (1958) Angew. Chem., 70, 738.
19.
De WaardA., PhillipsA.H., and BlochK. (1959) J. Am. Chem. Soc., 81, 2913–2914.
20.
PopjákG.J., and CornforthJ.W. (1966) Biochem. J., 101, 553–568.
21.
CornforthJ.W., and CornforthR.H. (1970) In: GoodwinT.W. (ed.), Natural substances formed biologically from mevalonic acid, pp. 5–15. Academic Press, London.
22.
CornforthJ.W., CornforthR.H., DonningerC., and PopjákG.J. (1966) Proc. R. Soc. Lond., Ser. B, 163, 492–514.
23.
CornforthJ.W., CornforthR.H., PopjákG.J., and YenguyanL. (1966) J. Biol. Chem., 241, 3970–3987.
24.
PopjákG.J., GoodmanD.W.S., CornforthJ.W., CornforthR.H., and RhyageR. (1961) J. Biol. Chem., 236, 1934–1937.
25.
CornforthJ.W., RossF.P., and WakselmanC. (1975) J. Chem. Soc., Perkin Trans.1, 429–431.
26.
CornforthJ.W., and GrayR.T. (1975) Tetrahedron, 31, 1509–1510.
27.
CornforthJ.W., CornforthR.H., and PopjákG.J. (1962) Tetrahedron, 18, 1351–1354.
