Ureteropelvic junction obstruction (UPJO) constitutes a significant cause of morbidity in children and exists in a wide range of severity and clinical manifestations. The cause of UPJO remains largely unknown except for a small group, in which crossing vessels have been considered etiological. Herein we describe a unique case in which intraluminal occlusion was the result of mucosal malformation, characterized by invaginated and branching urothelial epithelium present in the lamina propria. We believe that the present case is the first such description of this type of alteration.
HannaMKJeffsRDSturgessJMBarkinM. Ureteral structure and ultrastructure. Part II. Congenital ureteropelvic junction obstruction and primary obstructive megaureter. J Urol1976;116:725–730.
2.
StephensFD. Ureterovascular hydronephrosis and the “aberrant” renal vessels. J Urol1982;128:984–987.
3.
ZhangPLPetersCARosenS. Ureteropelvic junction obstruction: morphological and clinical studies. Pediatr Nephrol2000;14:820–826.
4.
HuangW-YPetersCAZurakowskiD. Renal biopsy in congenital ureteropelvic junction obstruction: evidence for parenchymal maldevelopment. Kidney Int2006;69:137–143.
Ruano-GilDCoca-PayerasATejedo-MateuA. Obstruction and normal recanalization of the ureter in the human embryo. Its relation to congenital ureteric obstruction. Eur Urol1975;1:287–293.
7.
DesmetVJ. Congenital diseases of intrahepatic bile ducts: variations on the theme “ductal plate malformation”. Hepatology1992;16:1069–1083.
