Three cases of persistent right umbilical vein associated with left-sided gallbladder are presented. This poorly understood, rare variant is due to obliteration of the left umbilical vein during embryonic development. The left-sided gallbladder, associated with persistent right umbilical vein, is not anomalous positioning of the gallbladder but an embryologic abnormality of the umbilical vein that causes the gallbladder to migrate to the left of the ligament teres. Findings and clinical relevance are discussed.
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