24 pazienti con sintomatologia clinica o diagnosi TC di processo espansivo cranio-encefalico o vertebro-midollare sono stati studiati con risonanza magnetica prima e dopo somministrazione endovenosa di Gadolinio-DTPA. Sono state quindi esaminate alcune caratteristiche della lesione neoplastica, quali identificazione, incremento di segnale dopo contrasto, definizione dei margini tumorali e dell'edema perifocale. Nella maggior parte dei casi, dopo iniezione di Gd-DTPA si è ottenuta una ottimale differenziazione tra tumore, edema perifocale e tessuto sano adiacente, in assenza di effetti collaterali. L'efficacia diagnostica e la buona tolleranza del Gd-DTPA ne giustificano l'uso come mezzo di contrasto in RM.
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