One new cembrane, ent -sinuflexibilin D (1), along with seven known compounds (2-8) were isolated from a population of Bornean soft coral Sinularia flexibilis. Their structures were elucidated on the basis of spectroscopic analyses. Cytotoxicity and antifungal activities of these compounds were evaluated in vitro. In addition, muurolene 7 was first isolates from a marine source.
TsaiTC, WuYJ, SuJH, LinWT, LinYS. (2013) A new spatane diterpenoid from the cultured soft coral Sinularia leptoclados. Marine Drugs, 11, 114–123.
2.
IwagawaT, NakashimaR, TakayamaK, OkamuraH, NakataniM, DoeM, ShibataK. (1999) New cembranes from the soft coral Sarcophyton species. Journal of Natural Products, 62, 1046–1049.
3.
SuCC, WongBS, ChinC, WuYJ, SuJH. (2013) Oxygenated cembranoids from the soft coral Sinularia flexibilis. International Journal of Molecula Sciences, 14, 4317–4325.
4.
WeinheimerAJ, MatsonJA, HossainMB, van der HelmD. (1977) Marine anticancer agents: sinularin and dihydrosinularin, new cembranolides from the soft coral, Sinularia flexibilis. Tetrahedron Letters, 34, 2923–2926.
5.
IshiiT, MatsuuraH, ZhaoqiZ, VairappanCS. (2009) A new norsesquiterpenoid from a Bornean soft coral genus Nephthea. Molecules, 14, 4591–4596.
6.
WenT, DingY, DengZ, van OfwegenL, ProkschP, LinW. (2008) Sinulaflexiolides A-K, cembrane-type diterpenoids from the Chinese soft coral Sinularia flexibilis. Journal of Natural Products, 71, 1133–1140.
7.
QinS, HuangH, GuoYW. (2008) A new cembranoid from the Hainan soft coral Sinularia sp. Journal of Asian Natural Products Research, 10, 1075–1079.
8.
HuLC, YenWH, SuJH, ChiangMYN, WenZH, ChenWF, LuTJ, ChangYW, ChenYH, WangWH, WuYC, SungPJ. (2013) Cembrane derivatives from the soft corals, Sinularia gaweli and Sinularia flexibilis. Marine Drugs, 11, 2154–2167.
9.
ShmulG, BenayahuY, KashmanY. (2007) Abruptoside A, a novel glycolipid from the Kenyan soft coral Sinularia abrupta. Natural Product Communications, 2, 51–54.
10.
SuHJ, LeeNL, LuMC, SuJH. (2012) Triangulene C, a new cubitane-based diterpenoid from the soft coral Sinularia triangula. Natural Product Communications, 7, 479–480.
11.
IshiiT, MatsuuraH, ZhaoqiZ, VairappanCS. (2009) A new 4a-methylated sterol from a Nephthea sp. (Nephtheidae) Bornean soft coral. Molecules, 14, 3360-3366.[12] WangLH, ChenKH, DaiCF, HwangTL, WangWH, WenZH, WuYC, SungPJ. (2014) New cembranoids from the soft coral Sinularia arborea. Natural Product Communications, 9, 361–362.
12.
LinYS, SuJH, LoCL, HuangCY, SheuJH. (2016) Isobicyclogermacrene-type sesquiterpenoids from the soft coral Sinularia lochmodes. Natural Product Communications, 11, 577–578.
13.
SuJH, HuangCY, LiPJ, LuY, WenZH, KaoYH, SheuJH. (2012) Bioactive cadinane-type compounds from the soft coral Sinularia scabra. Archives of Pharmacal Research, 35, 779–784.
14.
WeyerstahlP, MarschallH, WeirauchM, ThefeldK, SurburgH. (1998) Constituents of commercial labdanum oil. Flavour and Fragrance Journal, 13, 295 – 318.
15.
YangB, ZhouX, HuangH, YangXW, LiuJ, LinX, LiX, PengY, LiuY. (2012) New cembrane diterpenoids from a Hainan soft coral Sinularia sp. Marine Drugs, 10, 2023–2032.
MunchanC, HataiK, TakagiS, YamashitaA. (2009) In vitro and in vivo effectiveness of itraconazole against Ochroconis humicola isolated from fish. Aquaculture Science., 57, 399 – 404.
18.
LeeYN, HataiK, KurataO. (2017) Haliphthoros sabahensis sp. nov. isolated from mud crab Scylla tranquebarica eggs and larvae in Malaysia. Fish Pathology, 52, 31–37.
19.
HamadaT, WhiteY, NakashimaM, OisoY, FijitaMJ, OkamuraH, IwagawaT, ArimaN. (2012) The bioassay-guided isolation of growth inhibitors of adult T-cell leukemia (ATL), from the Jamaican plant Hyptis verticillata, and NMR characterization of hyptoside. Molecules, 17, 9931–9938.
20.
PhanCS, KamadaT, KobayashiK, HamadaT, VairappanCS. (2018) 15-Deoxy-isoxeniolide-A, new diterpenoid from a Bornean soft coral, Xenia sp. Natural Product Research, 32, 202–207.
