One new cembrane diterpene, 16-hydroxycembra-1,3,7,11-tetraene (1), along with three known compounds, 15-hydroxycembra-1,3,7,11-tetraene (2), sarcophine (3) and sarcophytoxide (4) were isolated from Sarcophyton sp. collected from Karah Island, Terengganu, West Malaysia. Their structures were elucidated based on spectroscopic data. Activities of these compounds against antibacterial resistant clinical bacteria are reported. Only 1 exhibited inhibition against Staphylococcus aureus.
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PhanCS, VairappanCS. (2015) Isopropyl(ene)-type cembrane diterpene an important chemotaxonomical marker in Bornean soft coral genus Sarcophyton. Journal of Tropical Biology and Conservation, 12, 137-143.
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ShaabanKA, GhaniMA, ShaabanM. (2015) New cembranoid diterpenes from Sarcophyton trocheliophorum. British Journal of Pharmaceutical Research, 5, 192-201.
