Sulfur compounds obtained from onion, Welsh onion, and garlic are reviewed. A major component (onionin A1) depressed tumor progression and metastasis in both osteosarcoma and ovarian cancer-bearing mouse models.
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2.
NoharaT., FujiwaraY., IkedaT., MurakamiK., OnoM., El-AasrM., NakanoD., KinjoJ. (2016) Two new bicyclic sulfoxides from Welsh onion. Journal of Natural Medicines, 70, 260–265.
3.
NoharaT., KiyotaY., SakamotoT., ManabeH., OnoM., IkedaT., FujiwaraY., NakanoD., KinjoJ. (2012) Garlicnins B1, C1, and D, from the fraction regulating macrophage activation of Allium sativum. Chemical and Pharmaceutical Bulletin, 60, 747–751.
4.
OnoM., FujiwaraY., IkedaT., PanC., El-AasrM., LeeJ.-H, NakanoD., KinjoJ., NoharaT. (2017) Atypical cyclic sulfides, garlicnins G, I, and J extracted from Allium sativum. Chemical and Pharmaceutical Bulletin, 65, 102–106.
5.
FujiwaraY., HorladH., ShiraishiD., TsubokiJ., KudoR., IkedaT., NoharaT., TakeyaM., KomoharaY. (2016) Onionin A, a sulfer-containing compound isolated from onion, impairs tumor development and lung metastasis by inhibiting the protumoral and immune-suppressive functions of myeloid cells. Molecular Nutrition & Food Research, 60, 2467–2480.
