Bioactivities of Chuquiraga Straminea Sandwith

Abstract

Methanolic extracts of Chuquiraga straminea Sandwith, subfamily Barnadesioideae (Asteraceae) showed the presence of quercetin-3-O-glucoside, quercetin-3-O-rutinoside, kaempferol, kaempferol-3-O-glucoside and kaempferol-3-O-rutinoside. Antioxidant and antimicrobial activity was determined. The total extracts showed antioxidant activity by DPPH and ABTS method (SC₅₀ 14.5 to 34.9 μg/mL). A significantly positive correlation was observed between the antioxidant activity and the total phenolics (R2>0.93). The extracts were active against ten methicillin resistant and sensitive Staphylococcus aureus strains isolated from nosocomial infection (MIC values between 200 to 800 μg/mL). These preliminary studies are highly interesting as they open new ways for further applications in the treatment of infections by methicillin resistant S. aureus.

Keywords

Flavonoids Chuquiraga straminea Antioxidant activity Antimicrobial activity

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