Sage Journals: Discover world-class research

Abstract

Childhood obesity continues to be a major public health concern in the United States. This work reviews the current understanding of the relationship between sleep duration and obesity among children and adolescents. A systematic search was conducted for papers published between January 2000 and July 2013 using keywords: (sleep) and (overweight or obesity or obese or body mass index or BMI or adiposity or body fat or fat) and (children or child or youth or teen or pediatric or adolescent or paediatric or childhood or adolescence or boy or girl). Reference lists of relevant articles and reviews or meta-analysis articles were checked to identify additional studies. Only empirical work and longitudinal studies that focused on children and adolescents were included in this review. The search identified 22 longitudinal studies. The majority of the reviewed studies support the presence of an inverse relationship between sleep duration and obesity. However, in some studies the relationship was not significant in adjusted analyses. Differences as a function of age and gender were also noted. Despite more than a decade of research, the debate on the association between sleep duration and obesity continues. Further research with repeated assessments, valid objective measures, and better control of potential confounding variables is warranted.

Keywords

obesity sleep duration children adolescent review

‘Studies conducted in the past decade have indicated the association of sleep deprivation and obesity.’

The rates of obesity among adolescents have tripled in the past 3 decades; currently more than one third of children and adolescents in the United States are overweight or obese.¹ Children and adolescents with a high body mass index (BMI) are more likely to become obese as adults^2,3 and are at risk for many chronic conditions such as high cholesterol, hypertension,⁴ diabetes,^5,6 metabolic syndrome, liver disease,⁷ and cancers, including breast and colorectal cancer.⁸ Obesity prevention efforts should therefore begin early in life to prevent high-risk conditions later in adulthood.

Several behavioral, environmental, and genetic factors contribute to overweight and obesity. Physical inactivity and unhealthy diet often referred to as the “Big Two,” have been the primary focus of past obesity prevention programs.⁹ However, recent studies have recognized other factors as possible causes of obesity.^10,11 Some of these potential influences include microorganisms, endocrine disruptors, pharmaceutical iatrogenesis, reduced variability of ambient temperatures, increased maternal age, intrauterine effects, and sleep debt.¹¹ Among these factors, sleep deprivation has received considerable attention in the recent years.

An estimated 50 to 70 million Americans of all ages suffer from sleep problems.¹² Sleep needs may vary among individuals; however, it is recommended that 10- to 17-year-olds receive an average of 8.5 to 9.25 hours of sleep each night, 5- to 10-year-olds receive 10 to 11 hours of night sleep, and 1- to 3-year-olds receive 12 to 14 hours of sleep.^13-15 However, research studies suggest that children and adolescents receive considerably less sleep than the recommended amount. In a national study, about 25% parents of 6- to 11-year-olds reported that their children did not receive adequate amount of sleep for their age.¹⁶ A survey in Rhode Island found that 26% of high school students slept 6.5 hours or less and only 15% reported sleeping 8.5 hours or more on school nights.¹⁷ Data from the 2007 Youth Risk Behavior Survey indicated that about 69% of high school students get less than 8 hours of sleep on school nights.¹⁸ Moreover, the average sleep duration decreases by about 40 to 50 minutes from ages 13 to 19 years.¹⁷ Increased academic demands, television watching, and social and recreational pressures may all contribute to decreased sleep duration during adolescence.^17,19

Studies conducted in the past decade have indicated the association of sleep deprivation and obesity. The exact mechanism by which sleep deprivation may lead to obesity is not known; however, researchers have proposed several possible pathways, including the effect of sleep deprivation on hormones, energy expenditure, and health behaviors. Sleep has an effect on the sympathetic nervous system and/or hypothalamic hormones.²⁰ Sleep deprivation is associated with low levels of leptin and high levels of ghrelin, which influences appetite regulation.^20-22 Sleep restriction is also associated with an increase in cortisol levels, which promote increased food intake and the accumulation of visceral fat in humans.²³ The second potential mechanism by which sleep restriction can contribute to obesity is by promoting behavior that causes weight gain.²⁴ Increased wakefulness may provide more time for eating in an obesogenic environment where food is readily available.²⁵ Often, lack of sleep is associated with sedentary activities like television watching, which might lead to weight gain due to increased snacking.^26,27 Finally, sleep deprivation may lead to reduced energy expenditure. Sleep restriction has been linked with reductions in the thyroid-stimulating hormone (TSH). Since TSH stimulates basal metabolic rate, reductions in TSH can be associated with reduced resting metabolism.²⁴ Furthermore, people with chronic sleep restriction experience fatigue and daytime sleepiness,²⁸ which may decrease their motivation to engage in physical activity.^25,29 It is also possible that these individuals might consume high-energy drinks and food to overcome fatigue.²⁴ Though majority of these studies have been conducted with adults, it is possible that similar mechanism influence the relationship between sleep and obesity among children and adolescents.

Several epidemiological studies have examined the association between sleep deprivation and obesity among children and adolescents. Some review articles have also been published on this topic. Magee and colleagues examined seven longitudinal studies conducted with children between 2004 and 2008; all 7 studies reported an association between short sleep duration and increased weight.³⁰ The most recent review article by Guidolin and Gradisar³¹ included only 2 longitudinal studies with adolescents; both studies reported no significant associations. Several new studies have been published since then that examined the relationship between sleep duration and obesity, and some of the recent articles did not find any significant associations. The purpose of this review is to present the current understanding of the relationship between sleep duration and obesity among children and adolescents. Given the nature of cross-sectional studies, it is difficult to interpret whether sleep duration causes weight gain, or whether overweight/obese children have reduced sleep. Therefore, in this review we present only longitudinal studies among children and adolescents.

Methods

A systematic search was conducted using the PubMed, Academic Search Premier, ERIC, Health Source, and CINAHL databases for articles published between January 2000 through July 2013 using keywords: (sleep) and (overweight or obesity or obese or body mass index or BMI or adiposity or body fat or fat) and (children or child or youth or teen or pediatric or adolescent or paediatric or childhood or adolescence or boy or girl). Only empirical work that examined the longitudinal association between sleep duration and obesity among children and adolescents (ie, age of participants at baseline less than 18 years) was included. Articles that included a measure for weight and sleep duration were selected for review. Articles that examined sleep quality but not sleep duration were excluded. Studies on participants with obstructive sleep apnea, sleep disordered breathing, and other medical issues were excluded. Furthermore, articles in a language other than English and duplicate studies were also excluded. Reference list of relevant articles and reviews or meta-analysis articles were also checked.

Results

The search identified 22 longitudinal studies. Ten studies were conducted within the United States and another 12 studies conducted internationally in countries including Australia, Canada, Europe, Korea, and New Zealand (Table 1).

Table 1.

Longitudinal Studies Examining the Association Between Sleep Duration and Overweight/Obesity.

First Author, Year, Location	Sample	Obesity Measure	Sleep Measure	Confounding Variables	Major Finding
Reilly 2005,⁴⁹ United Kingdom	N = 7758, 50.7% M, Baseline: 5 months to 3 years, FU at age 7 years	Objective, UK reference data 1990; OB: ≥95 PCT	Parent reported	Maternal education, smoking during pregnancy, age of mother at delivery, gender, birth weight, parity, season of birth, gestational age, no of fetuses, infant feeding, parent obesity, no of siblings, energy intake at 3 years, ethnicity, TV watching, time in care per day, dietary patterns	OR of OB at 7 years for <10.5 hours at 3 years = 1.45 (1.10-1.89); ref: ≥12 hours
Lumeng 2007, ³⁷ United States	N = 785, 50% M, Baseline third grade, FU at sixth grade	Objective, OW: ≥95 PCT	Mothers reported sleep each day (including naps)	Maternal education, gender, race, change in sleep duration, baseline BMI	OR of OW at sixth grade = 0.60 (0.36-0.99)
Snell 2007, ³² United States	N = 2281, 50% M, 1441 for final analysisBaseline: 3-12 years, FU at 8-18 years	Baseline: height measured + weight reported by caregiver; FU: Objective, international cutoffs	Time diaries filled by parents for younger children, older children filled themselves	Baseline BMI, gender, age, family income, parental education, race	Additional 1 hour of baseline sleep associated with 5.3% point decline in probability of being OW at FU. >11 hours sleep associated with 17.1% point decline in probability of being OW; ref: 9-9.9 hours; effect significant for younger, not older children
Landhuis 2008,⁵¹ New Zealand	N = 1037, 52% M, Baseline: 3 years, FU at age 32 years	Objective, OB: BMI ≥30	Parent reported at 5, 7, 9, 11 years; at 32 years; self-reported	BMI at age 5 years, childhood socioeconomic status, parental control, parent BMI, PA at 32 years, TV viewing from 5-32 years, current smoking, gender, sleep at 32 years	OR of OB for mean sleep at 5-11 years = 0.65 (0.43-0.97)
Taveras 2008,³⁸ United States	N = 915, 50% M, Baseline: 6 months, FU at age 3 years	Objective, OW: ≥95 PCT	Mother-reported sleep duration at 6 months, 1 year, 2 years, in 24-hour period; weighted average for sleep duration calculated	Maternal education, income, prepregnancy BMI, marital status, prenatal smoking history, breastfeeding, race, birth weight, 6-month weight for length z score, TV viewing, daily active play	OR of OW for <12 hours = 2.04 (1.07-3.91); ref: ≥12 hours
Touchette 2008,⁴⁰ Canada	N = 1138, 46.8% M, Baseline: 5 months, FU at age 6 years	Objective, international cutoffs	Mother-reported sleep at 2.5, 3.5, 4, 5, 6 years	Birth weight, preterm, gender, maternal smoking during pregnancy, weight at 5 months, parental education, single parent, weaning, no breastfeeding at 5 months, maternal immigrant status, napping at 2.5 years; at 6 years: TV, video games, PA, perception of overeating, snacking, eating sweets, snoring, income	OR of OW/OB for short persistent sleep = 4.2 (1.6-11.1); short persistent ≤10 hours until 6 years; ref: 11 hours persistent
Bell 2010,³³ United States	N = 1930, Baseline: 0-13 years, FU after 5 years	FU: BMI measured, Baseline: weight reported by parent, OW: >85 and < 95, OB: ≥95 PCT	Average nighttime sleep used to calculate age-normalized sleep scores	Age, sex, birth weight, father present, TV viewing, birth order, urban residence, race, income, maternal education, parent BMI, physical activity, baseline BMI for older cohort	Younger cohort (0-4 years): short baseline sleep associated with OW/OB at FU, OR = 1.80 (1.16-2.80); older cohort (5-13 years)—baseline sleep not significantly associated with FU weight status
Calamaro 2010,³⁴ United States	N = 13 568, 50.25% M, Baseline: 7th-12th grade, FU after 2 years	Self-reported height and weight, OB: ≥95 PCT	Self-reported	Age, race, gender, parental income, depression, obesity at wave I	OB at FU was not associated with baseline sleep duration, OR for <6 hours = 1.23 (0.71-2.15); ref: 8 to <11 hours
Rutters 2010,⁴¹ the Netherlands	N = 98, 55% M, Baseline 12 years, FU at 16 years	Objective, international cutoffs	Teen-reported hours of sleep at age 12-16 years	Baseline BMI at start of puberty, parent BMI, TV viewing, FTO allele genotype, Tanner stages	With progressive Tanner stages, BMI increases and sleep duration decreases in an interrelated way independent of confounders (R² = .38, P < .02)
Carter 2011,⁵² New Zealand	N = 244, 56% M, Baseline 3 years, FU at age 7 years	Objective	Parent-reported and accelerometer	Gender, maternal education, maternal BMI, income, ethnicity, smoking during pregnancy, physical activity, TV viewing, fruit-vegetable intake, noncore food intake, baseline BMI	For each additional hour of sleep, change in BMI from age 3 to 7 years is reduced by 0.39 (0.06-0.72)
Hiscock 2011,⁴² Australia	N = 3857 infants, and 3844 preschool children, FU after 2 years	Objective, international cutoffs	Total sleep duration included naps, Children’s Light Time-Use Diary	In longitudinal relationship, controlled for wave 1, sex, and BMI	Wave 1 sleep duration did not predict wave 2 BMI, nor did wave 1 BMI predict wave 2 sleep duration
Miller 2011,⁵⁵ United States	N = 11 400, 50% M, Baseline: kindergarten, FU fifth grade	Objective	Parent reported	Family meals, TV time, parent employment hours, single parent, food insecurity, school lunches and breakfast child ate, cafeteria, gymnasium, playground adequate, PE hours, recess hours, lunch hours, public school, school size, number of school days required to attend, percent minority population, gender, race, region of residence, US born, mother married at birth, mother worked before KG, siblings, received food stamps before KG, child activity, child’s early health, birth weight, preterm, participated in WIC	Each additional hour of sleep for children was associated with a .0644 decrease in initial BMI, but was not significantly associated with the rate of BMI change over time
Seegers 2011,³⁵ Canada	N = 1916, Baseline 6 years, FU at 13 years	Parent-reported height and weight	Parent-reported bedtime/waketime at 10, 11, 12, 13 years	Sex, maternal immigrant status, income, birth weight, parent education, pubertal status, TV time, PA	OR of OW = 1.51 (1.28-1.76); for OB = 2.07 (1.51-2.84) at 13 years with 1 hour less of sleep per night at 10 years of age
Silva 2011,³⁹ United States	N = 304, Baseline 6-12 years, FU after 5 years	Objective, CDC growth charts; OW ≥85th BMI, OB ≥95 BMI	Polysomnography	Baseline BMI, ethnicity, SDB, age, caffeine use, calorie expenditure, calorie intake, parental education, hours of television or video use	OR of OB = 3.3 (1.09-9.66) for <7.5 hours; ref >= 9 hours
Araujo 2012,⁵³ Portugal	N = 1171, Baseline 13 years, FU at age 17 years	Objective, CDC growth charts	Self-reported	Parental education and diet quality index, baseline BMI	Sleep duration at age 13 years was inversely associated with BMI z score b = 20.123 (20.23-20.01) at 17 years only in boys. Not significant after controlling adiposity at 13 years
Lee 2012,⁴⁸ Korea	N = 474 first graders, N = 1030 fourth graders, FU after 2 years	Objective, Korean reference charts	Self-reported	Age, sex, Tanner stages, baseline BMI, exercise, screen time, income, parent BMI, parent education, maternal job, family structure, energy intake, meal skip, snacking	OR for ≥9.5 hours = −0.463 (–0.87 to −0.05); ref: ≤8.5 hours
O’Dea 2012,⁴³ Australia	N = 939, Baseline 2-6 graders, 50% M; FU 4 years	Objective, International Obesity Task Force cutoffs	Parent- and child-reported weekday sleep and wake times	Gender, socioeconomic status, physical activity, baseline BMI	Children in the upper tertile of sleep in year 1 had a 2.3 kg lower weight gain (SE: 0.5) between years 1 and 4 (P < .0001) than children in the lower tertile of sleep and a 0.45 kg/m² lower increase in BMI (SE = 0.15; P = .004)
Storfer-Isser 2012,⁵⁴ United States	N = 313, 50% M, Baseline 8-11 years, FU at age 16-19 years	Objective, international cutoffs	Baseline parent-reported, FU teen-reported	Age, race, birth weight, socioeconomic status, baseline BMI	Sleep duration at age 8-11 years predicted BMI z for boys (B = −0.30, P = .02) but not girls. Not significant after controlling baseline BMI
Klingenberg 2013,⁵⁶ Denmark	N = 311, Baseline 9 months, FU at 3 years	Objective, WHO growth standard sex-adjusted body-mass-index-for-age z score	Parent-reported bedtime/waketime at 9 months, 18 months, and 3 years. Accelerometer at 3 years	Birth weight, gestational age, breastfeeding, maternal smoking, maternal BMI at 9 months, household income, parental education	No association between BMI z scores at 3 years and sleep duration at 9 months, 18 months, and 3 years
Lytle 2013,⁵⁰ United States	N = 723, Baseline mean age = 14.7 years. FU 2 years	Objective	Self-reported	Race, grade, parent education, school lunch, puberty, study, screen time/sedentary behavior, depression, activity, and energy intake	No statistically significant longitudinal relationship between change in total sleep and change in BMI over time in either girls or boys
Magee 2013,⁴⁴ Australia	N = 1079, Baseline age = 4-5 years, 51% M, FU 6 years	Objective, International Obesity Task Force definitions, BMI trajectories	24-hour time-use diaries completed by one parent on a weekday and a weekend day	Mother and father BMI, mother education, child birth weight	Sleep at 6 to 7 years was inversely associated with BMI at 8 to 9 years (b = −0.68, P = .017) and sleep at 8-9 years inversely associated with BMI at 10-11 yrs (b = −1.21, P = .003) in the early onset trajectory
Mitchell 2013,³⁶ United States	N = 1089, Baseline mean age = 14.3 years. 50% M; FU 4 years	Self-reported height, weight, BMI PCT	Self-reported, average night sleep	Gender, race, maternal education, screen time, self-reported PA	Each additional hour of sleep was associated with decreases in BMI at 25th = −0.12(−0.20 to −0.04), 50th = −0.15 (−0.24 to −0.06), 75th = −0.25 (−0.38 to −0.12), 90th = −0.27 (−0.45 to −0.09) BMI PCT

Abbreviations: BMI, body mass index; F, female; FU, follow-up; M, male; Objective, height and weight measured to calculate BMI; OB, obese; OR, odds ratio; OW, overweight; PCT, percentile; PA, physical activity; Ref, reference value.

A number of methodological differences were noted among the reviewed articles. Studies varied in their methods to collect data for BMI calculations. Objectively measured height and weight was used to calculate BMI in most of the studies, but in others height and/or weight information was obtained via self-report.^32-36 Studies also differed in the classification used to define overweight/obesity. Studies conducted in the United States used the 2000 Centers for Disease Control and Prevention (CDC) growth charts to calculate the BMI percentiles,^33,34,37-39 whereas the majority of studies conducted outside the United States used the international cutoff points.^40-44 The CDC growth charts were developed with data from the 5 national health examination surveys in the United States.⁴⁵ The international cutoffs were developed using the survey data from 6 countries (Brazil, Great Britain, Hong Kong, the Netherlands, Singapore, and the United States).⁴⁶ The use of CDC versus international cutoffs can result in an absolute difference of 0% to 13% in the prevalence of overweight and obesity.⁴⁷ Some other studies used their country-specific growth charts. For example, Lee et al⁴⁸ used the Korean growth charts and another study used the UK reference charts.⁴⁹ Furthermore, the differences in the classification of obesity status and the reference group used in the analyses could affect the relationship between sleep duration and obesity in the reviewed articles. For example, studies by Silva et al³⁹ and Bell and Zimmerman³³ analyzed the odds of being overweight (ie, BMI >85 kg/m²) and obese (BMI >95 kg/m²) compared with a reference group of normal weight participants (BMI <85 kg/m²), whereas, Calamaro et al³⁴ analyzed the odds of being obese (BMI >95 kg/m²) compared with a reference group of participants with BMI <95 kg/m². Including overweight participants in the reference group could affect the relationship between sleep and weight status.

The definition of short sleep duration differed among the reviewed articles, but seemed appropriate for the age-group examined in the studies. For example, Taveras et al³⁸ used <12 hours as short sleep duration for 6-month-olds, Reilly et al⁴⁹ used <10.5 hours for children 5 months to 3 years old, Silva et al³⁹ used <7.5 hours for 6- to 12-year-olds, and Calamaro et al³⁴ used <6 hours for 7th to 12th graders. Most of the studies used parental and/or self-reported measure for sleep. Only one study used the polysomnographic assessment for sleep.³⁹ Two studies included naps in the total sleep time.^37,42 However, no specific patterns were observed in the relationship between sleep and obesity based on these different sleep assessment techniques (Table 1). Finally, studies varied in the number and type of covariates controlled in the analyses. Most studies controlled for the demographic factors such as age, gender, and socioeconomic conditions; however, they varied in relation to the health-related behaviors such as dietary intake, sedentary habits, and physical activity. Very few studies controlled for puberty,^35,41,48,50 which is an important determinant of obesity among adolescents.

The reviewed studies used baseline sleep duration to predict overweight/obesity at a follow-up and thus can support a causal association between sleep and obesity. Most of these longitudinal studies indicated that short sleep duration is a risk factor for overweight/obesity.* The relationship was significant even after controlling for baseline weight status. Some of the studies have baseline data from the first year of life and follow up data until early childhood.^38,40,49 The longest longitudinal study to date was performed in New Zealand, where average sleep duration at 5 to 11 years of age was used to predict obesity in adulthood.⁵¹ The authors found that, with every one-hour increase in the sleep duration in childhood, the risk of obesity was reduced by 35% at 32 years of age.⁵¹

The longitudinal relationship between sleep duration and obesity in the reviewed articles varied as a function of age. In the study by Bell and Zimmerman³³ a significant association between sleep and obesity was seen only for younger children (0-4 years at baseline). Among older children (5-13 years), short sleep duration at baseline was not associated with weight gain at a 5-year follow-up. Similar results were found in the study by Snell et al.³² Some gender differences were also observed. Two reviewed studies noted the relationship between sleep duration and obesity among boys, but not among girls.^53,54

Some recently published studies (n = 7) did not support a longitudinal relationship between sleep duration and obesity.^{34,42,50,55,56} Using data from the National Longitudinal Study of Adolescent Health, Calamaro et al³⁴ found that short sleep among 7th to 12th graders was not associated with obesity at a 2-year follow-up. Two studies that examined the sleep duration of infants and obesity 2 to 3 years later did not find any significant association.^42,56 Miller et al found a concurrent relationship between sleep duration and obesity among children; however, the longitudinal association was not significant.⁵⁵ Similarly, Lytle et al⁵⁰ did not find any significant association between change in sleep duration and obesity risk in their longitudinal study of school children. Arauja et al⁵³ in Portugal and Storfer-Isser et al⁵⁴ in the United States found significant associations between baseline sleep duration and follow-up BMI z scores; however, the associations were not significant after controlling for baseline body composition.

Discussion

We conducted a comprehensive review of longitudinal studies examining the relationship between sleep duration and obesity among children and adolescents. This study represents an updated and expanded review from earlier work.^30,31 The current review includes more recently published longitudinal studies and those specifically focused on children and adolescents. A total of 22 studies were reviewed. The majority (n = 13) of the reviewed studies support an inverse relationship between sleep duration and obesity. Two studies found a significant association for younger children but not for older children.^32,33 However, seven longitudinal studies did not find the relationship between sleep duration and obesity to be significant in the adjusted analyses, especially after controlling for baseline body composition.^{34,42,50,53-56} This raises the question of publication bias in the earlier years of research in this field. Since we did not include unpublished papers, it is possible that we may have missed studies with nonsignificant findings.

The reviewed articles used different methodological approaches, including informants, collection and measurement of BMI and sleep, and used different covariates, which makes comparison of studies difficult. Comparing studies across the different developmental periods, we observed that findings differed as a function of age and gender. Five studies used baseline data from infants; two of these studies did not find significant relationship.^42,56 Three^42,54,55 of the 14 studies that reported data on children and six^{32-34,50,53,54} of the 10 studies that reported data on adolescents did not find significant association between the sleep duration and overweight/ obesity. Two studies noted positive associations among boys but not among girls.^53,54 These age and gender differences might be because of the physiological changes during puberty; however, more empirical research is needed to examine these physiological changes, including the effect on the sympathetic nervous system and hypothalamic hormones. Studies are needed that examine developmental variables such as puberty in the association between sleep and obesity. Pubertal development is associated with prominent changes in the body composition with attainment of more body fat in girls and more lean body mass, skeletal mass, and muscle mass in boys.⁵⁷ Moreover, these changes in body composition occur several years earlier in girls than in boys.⁵⁷ Without controlling for these developmental changes, the association between sleep duration and obesity may be biased. Whether this relationship varies as a function of age and gender or is related to the pubertal growth needs further exploration. Longitudinal studies with repeated assessments from early childhood to late adolescence may help to identify the critical window of development when sleep duration is a risk or protective factor for obesity. It is also possible that factors such as sleep quality, and shift in sleep times (ie, late bed and wake-up times) may play a role along with sleep duration. Furthermore, the role of daytime nap and catch-up sleep over weekends and holidays needs to be explored.

Obesity is caused by a number of complex and interrelated factors. The efficacy of an obesity prevention program targeting a single factor is relatively small.⁵⁸ Therefore, interventions that focus only on diet and/or physical activity have shown moderate success.^59,60 Under these circumstances, the role of short sleep in the obesity epidemic if supported can have great public health implications. However, it is important to realize that improving sleep alone will not be sufficient to reverse the obesity epidemic. The significance of adequate sleep does not undervalue the role of diet and physical activity. However, promoting adequate sleep along with the dietary and physical activity interventions may improve the efficacy of current programs. The Institute of Medicine has recently recommended the promotion of age-appropriate sleep duration as a measure of childhood obesity prevention.⁶¹ Short sleep duration in children and adolescents is primarily due to modifiable lifestyle factors. Parents, caregivers, and health care providers can help children to maintain good sleeping practices. Assessment of sleep patterns can be incorporated as a routine practice during clinic visits. Educational materials recommending the required amounts of sleep and methods to achieve it can be provided by primary care providers to parents and children. Parental monitoring may improve sleep habits among children and adolescents. Parents can be encouraged to put their younger kids to bed early. Setting rules about television and computer time can facilitate early bedtimes among adolescents.

Despite more than a decade of research, the debate on the causal association between sleep duration and obesity continues. To validate these relationships, longitudinal studies with repeated assessments, long-term exposure, measures of body composition, valid objective measures of sleep duration and sleep quality, and better control of confounders, including pubertal development, are required.⁶² Finally, the gold standard, randomized clinical trials, in which obese children and adolescents are encouraged to sleep for adequate hours, may more definitively establish causal pathways.

Footnotes

Authors’ Note

This work was conducted as part of doctoral dissertation of the first author at the University of Alabama at Birmingham.

*

References 35, 37, 43, 44, 48, 49, 51, .

References

Ogden

Carroll

Curtin

Lamb

Flegal

. Prevalence of high body mass index in US children and adolescents, 2007-2008. JAMA. 2010;303:242-249.

Guo

Chumlea

Roche

. Predicting overweight and obesity in adulthood from body mass index values in childhood and adolescence. Am J Clin Nutr. 2002;76:653-658.

Serdula

Ivery

Coates

Freedman

Williamson

Byers

. Do obese children become obese adults? A review of the literature. Prev Med. 1993;22:167-177.

Freedman

Dietz

Srinivasan

Berenson

. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics. 1999;103(6 pt 1):1175-1182.

Pinhas-Hamiel

Zeitler

. Insulin resistance, obesity, and related disorders among black adolescents. J Pediatr. 1996;129:319-320.

Shaibi

Goran

. Examining metabolic syndrome definitions in overweight Hispanic youth: a focus on insulin resistance. J Pediatr. 2008;152:171-176.

Cruz

Shaibi

Weigensberg

Spruijt-Metz

Ball

Goran

. Pediatric obesity and insulin resistance: chronic disease risk and implications for treatment and prevention beyond body weight modification. Annu Rev Nutr. 2005;25:435-468.

Calle

Kaaks

. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer. 2004;4:579-591.

Chaput

Sjodin

Astrup

Despres

Bouchard

Tremblay

. Risk factors for adult overweight and obesity: the importance of looking beyond the ‘big two’. Obes Facts. 2010;3:320-327.

10.

Keith

Redden

Katzmarzyk

. Putative contributors to the secular increase in obesity: exploring the roads less traveled. Int J Obes (Lond). 2006;30:1585-1594.

11.

McAllister

Dhurandhar

Keith

. Ten putative contributors to the obesity epidemic. Crit Rev Food Sci Nutr. 2009;49:868-913.

12.

National Center on Sleep Disorders Research. National Sleep Disorders Research Plan, 2003. Bethesda, MD: National Institute of Health; 2003.

13.

Carskadon

Acebo

Jenni

. Regulation of adolescent sleep: implications for behavior. Ann N Y Acad Sci. 2004;1021:276-291.

14.

Mercer

Merritt

Cowell

. Differences in reported sleep need among adolescents. J Adolesc Health. 1998;23:259-263.

15.

National Sleep Foundation. Children and sleep. 2013. http://www.sleepfoundation.org/article/sleep-topics/children-and-sleep. Accessed April 20, 2014.

16.

Smaldone

Honig

Byrne

. Sleepless in America: inadequate sleep and relationships to health and well-being of our nation’s children. Pediatrics. 2007;119(suppl 1):S29-S37.

17.

Wolfson

Carskadon

. Sleep schedules and daytime functioning in adolescents. Child Dev. 1998;69:875-887.

18.

Eaton

McKnight-Eily

Lowry

Perry

Presley-Cantrell

Croft

. Prevalence of insufficient, borderline, and optimal hours of sleep among high school students—United States, 2007. J Adolesc Health. 2010;46:399-401.

19.

Johnson

Cohen

Kasen

First

Brook

. Association between television viewing and sleep problems during adolescence and early adulthood. Arch Pediatr Adolesc Med. 2004;158:562-568.

20.

Spiegel

Tasali

Penev

Van Cauter

. Brief communication: sleep curtailment in healthy young men is associated with decreased leptin levels, elevated ghrelin levels, and increased hunger and appetite. Ann Intern Med. 2004;141:846-850.

21.

Chaput

Després

Bouchard

Tremblay

. Short sleep duration is associated with reduced leptin levels and increased adiposity: results from the Quebec family study. Obesity (Silver Spring). 2007;15:253-261.

22.

Taheri

Lin

Austin

Young

Mignot

. Short sleep duration is associated with reduced leptin, elevated ghrelin, and increased body mass index. PLoS Med. 2004;1(3):e62.

23.

Bjorntorp

. Do stress reactions cause abdominal obesity and comorbidities? Obes Rev. 2001;2:73-86.

24.

Magee

Huang

Iverson

Caputi

. Examining the pathways linking chronic sleep restriction to obesity. J Obes. 2010;2010. pii: 821710.

25.

Chaput

. Short sleep duration promoting overconsumption of food: a reward-driven eating behavior? Sleep. 2010;33:1135-1136.

26.

Patel

. Reduced sleep as an obesity risk factor. Obes Rev. 2009;10(suppl 2):61-68.

27.

Magee

Caputi

Iverson

. Lack of sleep could increase obesity in children and too much television could be partly to blame. Acta Paediatr. 2014;103:e27-e31.

28.

Durmer

Dinges

. Neurocognitive consequences of sleep deprivation. Semin Neurol. 2005;25:117-129.

29.

Resnick

Carter

Aloia

Phillips

. Cross-sectional relationship of reported fatigue to obesity, diet, and physical activity: results from the third national health and nutrition examination survey. J Clin Sleep Med. 2006;2:163-169.

30.

Magee

Hale

. Longitudinal associations between sleep duration and subsequent weight gain: a systematic review. Sleep Med Rev. 2012;16:231-241.

31.

Guidolin

Gradisar

. Is shortened sleep duration a risk factor for overweight and obesity during adolescence? A review of the empirical literature. Sleep Med. 2012;13:779-786.

32.

Snell

Adam

Duncan

. Sleep and the body mass index and overweight status of children and adolescents. Child Dev. 2007;78:309-323.

33.

Bell

Zimmerman

. Shortened nighttime sleep duration in early life and subsequent childhood obesity. Arch Pediatr Adolesc Med. 2010;164:840-845.

34.

Calamaro

Park

Mason

. Shortened sleep duration does not predict obesity in adolescents. J Sleep Res. 2010;19:559-566.

35.

Seegers

Petit

Falissard

. Short sleep duration and body mass index: a prospective longitudinal study in preadolescence. Am J Epidemiol. 2011;173:621-629.

36.

Mitchell

Rodriguez

Schmitz

Audrain-McGovern

. Sleep duration and adolescent obesity. Pediatrics. 2013;131:e1428-e1434.

37.

Lumeng

Somashekar

Appugliese

Kaciroti

Corwyn

Bradley

. Shorter sleep duration is associated with increased risk for being overweight at ages 9 to 12 years. Pediatrics. 2007;120:1020-1029.

38.

Taveras

Rifas-Shiman

Oken

Gunderson

Gillman

. Short sleep duration in infancy and risk of childhood overweight. Arch Pediatr Adolesc Med. 2008;162:305-311.

39.

Silva

Goodwin

Parthasarathy

. Longitudinal association between short sleep, body weight, and emotional and learning problems in Hispanic and Caucasian children. Sleep. 2011;34:1197-1205.

40.

Touchette

Petit

Tremblay

. Associations between sleep duration patterns and overweight/obesity at age 6. Sleep. 2008;31:1507-1514.

41.

Rutters

Gerver

Nieuwenhuizen

Verhoef

Westerterp-Plantenga

. Sleep duration and body-weight development during puberty in a Dutch children cohort. Int J Obes (Lond). 2010;34:1508-1514.

42.

Hiscock

Scalzo

Canterford

Wake

. Sleep duration and body mass index in 0-7-year olds. Arch Dis Child. 2011;96:735-739.

43.

O’Dea

Dibley

Rankin

. Low sleep and low socioeconomic status predict high body mass index: a 4-year longitudinal study of Australian schoolchildren. Pediatr Obes. 2012;7:295-303.

44.

Magee

Caputi

Iverson

. The longitudinal relationship between sleep duration and body mass index in children: a growth mixture modeling approach. J Dev Behav Pediatr. 2013;34:165-173.

45.

Kuczmarski

Ogden

Guo

. 2000 CDC Growth Charts for the United States: methods and development. Vital and Health Statistics. Series 11, Data from the National Health Survey. May 2002;(246):1-190.

46.

Cole

Bellizzi

Flegal

Dietz

. Establishing a standard definition for child overweight and obesity worldwide: international survey. BMJ. 2000;320:1240-1243.

47.

Tuan

Butte

Nicklas

. Body mass index distribution affects discrepancies in weight classifications in children. Pediatr Int. 2012;54:256-265.

48.

Lee

Park

Kang

. Factors related to body mass index and body mass index change in Korean children: preliminary results from the obesity and metabolic disorders cohort in childhood. Korean J Fam Med. 2012;33:134-143.

49.

Reilly

Armstrong

Dorosty

; Avon Longitudinal Study of Parents and Children Study Team. Early life risk factors for obesity in childhood: cohort study. BMJ. 2005;330:1357.

50.

Lytle

Murray

Laska

Pasch

Anderson

Farbakhsh

. Examining the longitudinal relationship between change in sleep and obesity risk in adolescents. Health Educ Behav. 2013;40:362-370.

51.

Landhuis

Poulton

Welch

Hancox

. Childhood sleep time and long-term risk for obesity: a 32-year prospective birth cohort study. Pediatrics. 2008;122:955-960.

52.

Carter

Taylor

Williams

Taylor

. Longitudinal analysis of sleep in relation to BMI and body fat in children: the FLAME study. BMJ. 2011;342:d2712.

53.

Araujo

Severo

Ramos

. Sleep duration and adiposity during adolescence. Pediatrics. 2012;130:e1146-e1154.

54.

Storfer-Isser

Patel

Babineau

Redline

. Relation between sleep duration and BMI varies by age and sex in youth age 8-19. Pediatr Obes. 2012;7:53-64.

55.

Miller

. Associations between the home and school environments and child body mass index. Soc Sci Med. 2011;72:677-684.

56.

Klingenberg

Christensen

Hjorth

. No relation between sleep duration and adiposity indicators in 9-36 months old children: the SKOT cohort. Pediatr Obes. 2013;8:e14-e18.

57.

Styne D

Puberty

. In: Gardner

Shoback

, eds. Greenspan’s Basic & Clinical Endocrinology. 9th ed. New York, NY: McGraw-Hill; 2011:527-552.

58.

Chaput

. Short sleep duration as a cause of obesity: myth or reality? Obes Rev. 2011;12:e2-e3.

59.

Kamath

Vickers

Ehrlich

. Clinical review: behavioral interventions to prevent childhood obesity: a systematic review and meta-analyses of randomized trials. J Clin Endocrinol Metab. 2008;93:4606-4615.

60.

Harris

Kuramoto

Schulzer

Retallack

. Effect of school-based physical activity interventions on body mass index in children: a meta-analysis. CMAJ. 2009;180:719-726.

61.

Institute of Medicine. Early childhood obesity prevention policies. In: Birch

Parker

Burns

, eds. Washington DC: National Academic Press; 2011:1-190.

62.

Cappuccio

Taggart

Kandala

. Meta-analysis of short sleep duration and obesity in children and adults. Sleep. 2008;31:619-626.

Does Short Sleep Lead to Obesity Among Children and Adolescents? Current Understanding and Implications

Abstract

Keywords

Methods

Results

Discussion

Footnotes

Authors’ Note

*

References