Antemortem diagnosis of metastatic endometrial adenocarcinoma using computed tomography in a Vietnamese Pot-bellied sow

Abstract

A 13-y-old Vietnamese Pot-bellied sow (Sus scrofa) was presented because of blood-tinged mucoid vulvar discharge of 5-d duration and a 4-mo history of intermittent coughing and weight loss. Computed tomography revealed diffuse, multilobulated cystic and mineralized uterine masses, numerous lung nodules, and abdominal lymphadenopathy. Malignant neoplasia was suspected. Gross and histologic findings were diffuse cystic endometrial hyperplasia and endometrial adenocarcinoma of the mid-body of the left uterine horn. Metastatic foci were evident in the lungs, liver, and spleen. Neoplastic cells were immunoreactive for pan-cytokeratin. Metastatic endometrial adenocarcinoma and diffuse cystic endometrial hyperplasia have not been previously reported antemortem using computed tomography in a sow, to our knowledge.