Despite an increased reliance on immigrants to fill important jobs within the United States, research is lacking with regard to job satisfaction among immigrant employees. Using data from the 2002 and 2008 National Study of the Changing Workforce (n = 559), the authors examined how immigrant status affects determinants of job satisfaction. Hierarchical linear regression was used to uncover whether income satisfaction, autonomy, learning opportunities, supervisor, and coworker support predict U.S.-born and immigrant workers’ job satisfaction and how immigrant status moderates the relationship between each predictor and job satisfaction. Results showed the moderating effects of immigrant status for income satisfaction and autonomy on the job. The relationship between income satisfaction and job satisfaction was stronger for immigrants and the relationship between autonomy on the job and job satisfaction was negative for immigrants who lack English proficiency. These results add to the limited knowledge about the ever growing immigrant workforce within the United States.