Chronotype Influences Diurnal Variations in the Excitability of the Human Motor Cortex and the Ability to Generate Torque during a Maximum Voluntary Contraction

Abstract

The ability to generate torque during a maximum voluntary contraction (MVC) changes over the day. The present experiments were designed to determine the influence of an individual's chronotype on this diurnal rhythm and on cortical, spinal, and peripheral mechanisms that may be related to torque production. After completing a questionnaire to determine chronotype, 18 subjects (9 morning people, 9 evening people) participated in 4 data collection sessions (at 09:00, 13:00, 17:00, and 21:00) over 1 day. We used magnetic stimulation of the cortex, electrical stimulation of the tibial nerve, electromyographic (EMG) recordings of muscle activity, and isometric torque measurements to evaluate the excitability of the motor cortex, the spinal cord, and the torque-generating capacity of the triceps surae (TS) muscles. We found that for morning people, cortical excitability was highest at 09:00, spinal excitability was highest at 21:00, and there were no significant differences in TS EMG or torque produced during MVCs over the day. In contrast, evening people showed parallel increases in cortical and spinal excitability over the day, and these were associated with increased TS EMG and MVC torque. There were no differences at the level of the muscle over the day between morning and evening people. We propose that the simultaneous increases in cortical and spinal excitability increased central nervous system drive to the muscles of evening people, thus increasing torque production over the day. These differences in cortical excitability and performance of a motor task between morning and evening people have implications for maximizing human performance and highlight the influence of chronotype on an individual's diurnal rhythms.