This study compares the relationship between serum IgE and salivary Cortisol levels in 42 normal and in 18 type I allergic subjects. Levels of serum total IgE and salivary Cortisol were determined with the UniCAP system and ELISA respectively. In the type I allergic subjects, there was a significant correlation between serum IgE and salivary Cortisol levels (p < 0.01). In the normal subjects, on the other hand, no correlation was found. These findings suggest that there may be an association between stress and allergic disorders.
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