Impact of preoperative arterial stiffness index on graft patency following peripheral arterial bypass surgery

Abstract

Introduction:

We aimed to investigate the impact of preoperative Arterial Stiffness Index (ASI) values on primary graft patency following peripheral arterial bypass surgery.

Methods:

This retrospective cohort study included 92 patients who underwent femoro-popliteal bypass surgery between January 2019 and November 2024. Preoperative ASI values were measured using the Vasolab 5000 device. Patients were divided into two groups based on an ASI cut-off value of 10.0. Primary graft patency rates, Kaplan-Meier survival analysis, and multivariate Cox regression were performed to assess the relationship between ASI and graft outcomes.

Results:

Patients with ASI >10.0 exhibited significantly lower 12-month primary graft patency rates compared to those with ASI ⩽10.0 (61.9% vs 88.0%, p = 0.008). Multivariate Cox regression analysis identified high ASI as an independent predictor of graft failure (HR: 2.15; 95% CI: 1.15–4.03; p = 0.016), along with diabetes mellitus and the use of synthetic graft material.

Conclusion:

Preoperative ASI values are independently associated with primary graft patency after peripheral arterial bypass surgery. Arterial stiffness assessment may serve as a useful non-invasive tool for risk stratification in vascular surgery candidates.