Abstract
In a random crossover study in general practice, sixty patients with heart failure were given one week's maintenance treatment with the recommended dosage of Burinex K or Lasix + K. Burinex K appeared to be easier to swallow than the supplement tablets of Lasix + K although the differences were not significant.
Patients showed a highly significant preference to take two tablets on one occasion (Burinex K) rather than two different types of tablet on three separate occasions (Lasix + K). Despite pharmacological arguments in favour of simultaneous versus separate administration of potassium supplement and diuretic, patient acceptability is of over-riding importance in the long-term.
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