Naftidrofuryl (Praxilene) has been shown experimentally to improve the metabolism of brain cells where this has been impaired by advancing ischaemia due to arteriosclerosis. It has been evaluated in warded chronic patients showing signs of impaired intellectual ability. The trial was performed double-blind involving an identical placebo and the results assessed using psychometric tests and analyzed statistically. The results confirm the effectiveness of Naftidrofuryl (Praxilene) in improving intellectual performance and this was particularly apparent in the less severely affected.
Get full access to this article
View all access options for this article.
References
1.
EichhornO (1969) Du traitement des lésions vasculaires cérébrales. Med. Welt, 42, 2314
2.
FontaineLGrandMFoltzerS (1963) Enregistrement kymographique des variations du débit sanguin coronaire et périphérique par le rotamètre de Shipley-Wilson. Thérapie18, 1213
3.
FontainLGrandMChabertJSzarvasiEBayssatM (1968) Pharmacologie générale d'une substance nouvelle vasodilatatrice, le naftidrofuryl. Bulletin de Chimie Therapeutique6, 463
4.
FontaineLGrandMSzarvasiEBayssatM (1969) Etude de l'activité vasodilatatrice du Naftidrofuryl. Chimie Thérapeutique1, 39
5.
QuadbeckG (1969) Personal Communication
6.
SicardAMathivatAWeltiJ-JPerrinANataliJRanglaretACristolRFontaineLBattino etJ (1968) Le Naftidrofuryl, Vaso-dilatateur périphérique. La Presse Médicale76, 1015