X-ray imaging plays a crucial role in the diagnosis of pathology of virtually every organ system of the human body. It has provided a crucial insight into the pathogenesis and patho-physiology of many diseases. Radiological modalities have been used as a measure of drug efficacy and an objective means of comparing various drug regimens. This article describes the current role of X-ray imaging in the development of drugs and outlines the possibilities in the future.
LenchikLSartorisDJCurrent concepts in osteoporosis: Review article. Am J Roentgen. 1997;168: 905–911.
2.
BlakeGMGluerCCFogelmanI.Bone densitometry: Current status and future prospects. Br J Radiol. 1997;70:177–186.
3.
BraggDGMurrayKATrippD.Experiences with computed tomography: can we afford the cost?Am J Roentgen. 1997;169:935–941.
4.
HounsfieldGNComputerized transverse axial scanning (tomography). I. Description of the system. Br J Radiol. 1973;46:1016–1022.
5.
TammingaCAConleyRRThe application of neuroimaging techniques to drug development. J Clin Psych. 1997;58(suppl 10):3–6.
6.
MayoJRWebbWRGouldRHigh resolution CT of the lungs: An optimal approach. Radiol. 1987;163:507–510.
7.
BrinkJATechnical aspects of helical CT. Radiol Clin North Am.1995;33:825–841.
8.
BrinkJAHelicalCT: Principles, techniques and clinical applications: introduction. Radiographics. 1994;14:887–893.
9.
HunterGJHambergLMPonzoJAAssessment of cerebral perfusion and arterial anatomy in hyperacute stroke with three dimensional CT: Early clinical results. Am J Neuroradiol1998;19(1): 29–37.
10.
KummerRVAcute stroke: Usefulness of early CT findings before thrombolytic therapy. Radiol. 1997;205:327–333.
11.
MacVicarDHusbandJEAssessment of response following treatment of malignant disease. Br J Radiol. 1997;70:41–49.
12.
PasseTJBluemkeDASiegelmanSSTumor angiogenesis: Tutorial on implications for imaging. Radiol. 1997;203:593–600.
13.
PrattWBThe Anticancer Drugs. Second edition. Oxford: Oxford University Press; 1994:265–284.