The rate of comorbid attention-deficit hyperactivity disorder and bipolar disorder far exceeds chance if the two are independent conditions. Explanations for such a high comorbid prevalence and management implications are considered.
BerksonJ (1946) Limitations of the application of fourfold table analysis to hospital data. Biometrics2: 47–53.
2.
KlassenLJKatzmanMAChokkaP (2010) Adult ADHD and its comorbidities, with a focus on bipolar disorder. Journal of Affective Disorders124: 1–8.
3.
MarangoniCDe ChiaraLFaeddaGL (2015) Bipolar disorder and ADHD: Comorbidity and diagnostic distinctions. Current Psychiatry Reports17: 604.
4.
Martinez-AranAVietaEReinaresM, et al. (2004) Cognitive function across manic or hypomanic, depressed, and euthymic states in bipolar disorder. American Journal of Psychiatry61: 262–270.
5.
MilbergerSBiedermanJFaraoneSV, et al. (1995) Attention deficit hyperactivity disorder and comorbid disorders: Issues of overlapping symptoms. American Journal of Psychiatry152: 1793–1799.
6.
NierenbergAAMiyaharaSSpencerT, et al. (2005) Clinical and diagnostic implications of lifetime attention-deficit/hyperactivity disorder comorbidity in adults with bipolar disorder: Data from the first 1000 STEP-BD participants. Biological Psychiatry57: 1467–1473.
7.
NunezNACoombesBJRomo-NavaF, et al. (2022) Clinical and genetic correlates of bipolar disorder with childhood-onset attention deficit disorder. Frontiers in Psychiatry13: 884217.
8.
PatakiCCarlsonGA (2013) The comorbidity of ADHD and bipolar disorder: Any less confusion?Current Psychiatry Reports15: 372.
9.
PerroudNCorderaPZimmermannJ, et al. (2014) Comorbidity between attention deficit hyperactivity disorder (ADHD) and bipolar disorder in a specialized mood disorders outpatient clinic. Journal of Affective Disorders168: 161–166.
10.
SachsGSBaldassanoCFTrumanCJ, et al. (2000) Comorbidity of attention deficit hyperactivity disorder with early- and late-onset bipolar disorder. American Journal of Psychiatry157: 466–468.
11.
SchiweckCArteaga-HenriquezGAichholzerM, et al. (2021) Comorbidity of ADHD and adult bipolar disorder: A systematic review and meta-analysis. Neuroscience & Biobehavioral Reviews124: 100–123.
12.
StateRCFryeMAAltshulerLL, et al. (2004) Chart review of the impact of attention-deficit/hyperactivity disorder comorbidity on response to lithium or divalproex sodium in adolescent mania. Journal of Clinical Psychiatry65: 1057–1063.
13.
TamamLKarakusGOzpoyrazN (2008) Comorbidity of adult attention-deficit hyperactivity disorder and bipolar disorder: Prevalence and clinical correlates. European Archives of Psychiatry and Clinical Neuroscience258: 385–393.
14.
YoungstromEAEugeneALFrazierTW (2010) Bipolar and ADHD comorbidity: Both artifact and outgrowth of shared mechanisms. Clinical Psychology and Practice17: 350–359.