Background
The Oxfordshire Community Stroke Project (OCSP) clinical classification of subtypes of cerebral infarction reported to be simple and practicable. The large database of cerebral infarction is available in Okinawa, Japan.
Purpose
The aim of the study was to evaluate acute and long-term prognosis of cerebral infarction registered in Okinawa prefecture in 1998–1991 according to the OCSP classification.
Method
We divided total 2126 patients with cerebral infarction into the following 4 OCSP categories: total anterior circulation infarcts (TACI), partial anterior circulation infarcts (PACI), lacunar infarcts (LACI), and posterior circulation infarcts (POCI). Relative risks of death were examined by multivariate Cox proportional hazard analysis after adjusting age and sex.
Result
The comprised 202 patients (9. 5%) with TACI, 558 (26.2%) with PACI, 1188 (55.9%) with LACI, and 178 (8.4%) with POCI. The adjusted hazard ratio (95% CI) for the risk of death in 10-year observation was 1.07 (0.85–1.34) for POCI, 1.24 (1.16–1.33) for PACI, and 1.43 (1.35–1.53) for TACI, when compared to that in patients with LACI (1.00). The mortality rates within 28 days after the onset were 37.1% for TACI, 6.1% for PACI, 1.85% for LACI, and 5.6% for POCI.
Conclusion
The acute mortality rate of TACI was extensively high. The long-term prognosis of cerebral infarction differed among OCSP subgroups.