AlbaneseVTommasinoCSpadaroATomaselloF, (1980) A transbasisphenoidal approach for selective occlusion of the middle cerebral artery in rats. Experientia36:1302–1304
2.
AlpersBJBerryRGPaddisonRM, (1959) Anatomical studies of the circle of Willis in normal brain. Arch Neurol Psychiat81:409–418
3.
AstrupJ, (1982) Energy-requiring cell functions in the ischemic brain. Their critical supply and possible inhibition in protective therapy. J Neurosurg56:482–497
4.
AstrupJSiesjoBKSymonL, (1981) Thresholds in cerebral ischemia—the ischemic penumbra. Stroke12:723–725
5.
BedersonJBPittsLHTsujiMNichimuraMCDavisRLBartowskiH, (1986) Rat middle cerebral artery occlusion: Evaluation of the model and development of a neurological examination. Stroke17:472–476
6.
BrintSJacewiczMKiesslingMTanabeJPulsinelliW, (1988) Focal brain ischemia in the rat: Methods for reproducible neocortical infarction using tandem occlusion of the distal middle and ipsilateral common carotid arteries. J Cerceb Blood Flow Metab8:474–485
7.
BrownJO, (1966) The morphology of circulus arteriosus archi in rats. Anat Resc156:99–106
BrownAWBrierleyJB, (1972) Anoxic-ischaemic cell changes in rat brain: Light microscopic and fine structural observations. J Neurol Sci16:59–84
10.
BustoRDietrichWDGlobusMY-TValdézIScheinbergPGinsbergMD, (1987) Small differences in intraischemic brain temperature critically determine the extent of ischemic neuronal injury. J Cereb Blood Flow Metab7:729–738
11.
CammermeyerJ, (1961) The importance of avoiding “dark” neurons in experimental neuropathology. Acta Neuropathol1:245–270
12.
CoyleP, (1982) Middle cerebral artery occlusion in the young rat. Stroke13:855–859
13.
CoyleP, (1986) Different susceptibilities to cerebral infarction in spontaneously hypertensive and normotensive Sprague-Dawley rats. Stroke17:520–525
14.
CoylePOdenheimerDJSingCF, (1984) Cerebral infarction after middle cerebral artery occlusion in progenies of spontaneously stroke-prone and normal rats. Stroke15:711–716
15.
DuvergerDBenavidesJCudennecAMacKenzieETScattonBSeylazJVerrecchiaC, (1987) A glutamate antagonist reduces infarction size following focal cerebral ischaemia independently of vascular and metabolic changes. J Cereb Blood Flow Metab7:S144
16.
DuvergerDLecoffreCMacKenzieET, (1985) Histological quantification of cerebral infarction following middle cerebral artery occlusion in various rat strains. J Cereb Blood Flow Metab5:S415–S416
17.
DuvergerDMacKenzieET, (1988) The quantification of cerebral infarction following focal ischaemia in the rat: Influence of strain, arterial pressure, blood glucose concentration and age. J Cereb Blood Flow Metab8:449–461
18.
GarciaJC, (1984) Experimental ischemic stroke: A review. Stroke15:5–14
19.
GautierJC, (1983) Cerebral ischaemia in hypertension. In: RussellRWR, ed. Vascular Disease of the Central Nervous System, Churchill Livingstone, Edinburgh, pp. 224–244
20.
GelmersHJGorterKde WeerdtCJWiezerHJA, (1988) A controlled trial of nimodipine in acute ischemic stroke. N Engl J Med318:203–207
21.
GermanoIMBartkowskiHMCasselMEPittsLH, (1987) The therapeutic value of nimodipine in experimental cerebral ischemia. J Neurosurg67:81–87
22.
GisvoldSESteenPA, (1985) Drug therapy in brain ischaemia. Br J Anaesth57:96–109
23.
GottiBMacKenzieETYoungAR, (1984) The pharmacotherapy of focal cerebral ischemia—development of an experimental model. J Chron Dis Ther Res8:44–61
24.
GrottaJC, (1987) Current medical and surgical therapy for cerebrovascular disease. N Engl J Med317:1505–1516
25.
HakimAM, (1986) Cerebral acidosis in focal ischemia. II. Nimodipine and verapamil normalize cerebral pH following middle cerebral artery occlusion in the rat. J Cereb Blood Flow Metab6:676–683
26.
HarveyKRasmussenI, (1951) Occlusion of the middle cerebral artery. An experimental study. Arch Neurol Psychiat66:20–29
HudginsWRGarciaJH, (1970) Transorbital approach to the middle cerebral artery of the squirrel monkey: A technique for experimental cerebral infarction applicable to ultrastructural studies. Stroke1:107–111
29.
JonesTHMorawetzRBCrowellRMMarcouxFWFitzgibbonSJde GirolamiUOjemannRG, (1981) Thresholds of focal cerebral ischemia in awake monkeys. J Neurosurg54:773–782
30.
KannelWBWolfPA, (1983) Epidemiology of cerebrovascular disease. In: RussellRWR, ed. Cerebral Artarial Disease, Churchill Livingstone, Edinburgh, pp. 1–23
31.
MacKenzieETDuvergerDGottiBNowickiJ-P, (1986) Cerebral anti-ischaemic agents: Problems and approaches. In: KrieglsteinJ, ed. Pharmacology of Cerebral Isehaemia, Elsevier, Amsterdam, pp. 167–179
32.
Medical Research Council Working Party (1985) MRC trial of treatment of mild hypertension: Principal results. Br Med J291:97–104
33.
MeyerJSDenny-BrownD, (1957) The cerebral collateral circulation. I. Factors influencing collateral blood flow. Neurology7:447–458
34.
MohamedAAGotohOGrahamDIOsborneKAMcCullochJMendelowADTeasdaleGMHarperAM, (1985) Effect of pretreatment with the calcium antagonist Nimodipine on local cerebral blood flow and histopathology after middle cerebral artery occlusion. Ann Neurol18:705–711
35.
NakayamaHDietrichWDWatsonBDBustoRGinsbergMD, (1988) Photothrombotic occlusion of rat middle cerebral artery: Histopathological and hemodynamic sequence of acute recanalization. J Cereb Blood Flow Metab8:351–366
36.
NedergaardMDiemerNH, (1985) Influence of hyperglycemia on ischemic brain damage after middle cerebral artery (MCA) occlusion in the rat. J Cereb Blood Flow Metab5:S231–S232
37.
OsborneKAShigenoTBalarskyA-MFordIMcCullochJTeasdaleGMGrahamDI, (1987) Quantitative assessment of early brain damage in a rat model of focal cerebral ischaemia. J Neurol Neurosurg Psechiat50:402–410
38.
OzyurtEGrahamDIWoodruffGNMcCullochJ, (1988) Protective effect of glutamate antagonist, MK-801, in focal cerebral ischemia in the cat. J Cerei) Blood Flow Metab8:138–143
39.
PulsinelliWALevyDESigsbeeBSchererPPlumP, (1983) Increased damage after ischemic stroke in patients with hyperglycemia with or without established diabetes mellitus. Am J Med74:540–544
40.
RiggsHERuppC, (1963) Variation in form of circle of Willis. Ach Neurol8:24–30
41.
RobinsonRG, (1981) A model for the study of stroke using the rat. Surgical ligation of the middle cerebral artery in the rat. Am J Pathol104:103–105
42.
SloanMA, (1987) Thrombolysis and stroke. Arch Neurol44:748–768
43.
SpetzlerRFNehlsDG, (1987) Cerebral protection against ischemia. In: WoodJH, ed. Cerebral Blood Flow: Phasiologic and Cliniaal Aspects. McGraw-Hill, New York, pp. 651–676
44.
SundtTMWaltzAG, (1966) Experimental cerebral infarction: Retro-orbital, extradural approach for occluding the middle cerebral artery. Mayo Clin Proc41:159–168
45.
SuzukiJYoshimotoTTanakaSSakamotoT, (1980) Production of various models of cerebral infarction in the dog by means of occlusion of intracranial trunk arteries. Staoke11:337–341
46.
TamuraAGrahamDIMcCullochJTeasdaleGM, (1981) Focal cerebral ischaemia in the rat. I. Description of technique and early neuropathological consequences following middle cerebral artery occlusion. J Cereb Blood Flow Metab1:53–60
47.
UK-TIA Study Group (1988) United Kingdom transient ischaemic attack (UK-TIA) aspirin trial: Interim results. Br Med J296:316–320
48.
VenablesGSMillerSAGibsonGHardyJAStrongAJ, (1985) The effects of hyperglycaemia on changes during reperfusion following focal cerebral ischaemia in the cat. J Neurol Neurosurg Psechiat48:663–669
49.
WeinsteinPRAndersonGGTellesDA, (1986) Neurological deficit and cerebral infarction after temporary middle cerebral artery occlusion in unanaesthetized cats. Staoke17:318–327
50.
WolfPAKannelWBMcGeeDL, (1986) Epidemiology of strokes in North America. In: BarnettHJMMoirJPSteinBMYatsuFM, eds. Staoke: Pathology, Diagnosia and Management. Churchill Livingstone, Edinburgh, pp. 19–29
51.
YatsuFMPettigrewLCGrottaJC, (1987) Medical therapies for acute stroke. In: WoodJH, ed. Cerebral Blood Bow: Phasiologic and Clinical Aspects. McGraw-Hill, New York, pp. 603–612