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Articles (12)

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1-10 of 12 results for synthetic lethal screen

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Select article: Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens

Free access

Research article

First published 2016-10

Ranking Differential Drug Activities from Dose-Response Synthetic Lethality Screens

Rajarshi Guha, Lesley A. Mathews Griner, Jonathan M. Keller [...]

Journal of Biomolecular Screening

Select article: VHL Synthetic Lethality Signatures Uncovered by Genotype-Specific CRISPR-Cas9 Screens

Retricted access

Research article

First published 2019-08

VHL Synthetic Lethality Signatures Uncovered by Genotype-Specific CRISPR-Cas9 Screens

Ning Sun, Sakina Petiwala, Charles Lu [...]

The CRISPR Journal

Select article: Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition

Free access

Research article

First published 2021-8

Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 Inhibition

Lick Pui Lai, Viviane Brel, Kanika Sharma [...]

Journal of Biomolecular Screening

Select article: A High-Throughput Screen with Isogenic PTEN +/+ and PTEN −/− Cells Identifies CID1340132 as a Novel Compound That Induces Apoptosis in PTEN and PIK3CA Mutant Human Cancer Cells

Free access

Research article

First published 2011-4

A High-Throughput Screen with Isogenic PTEN +/+ and PTEN −/− Cells Identifies CID1340132 as a Novel Compound That Induces Apoptosis in PTEN and PIK3CA Mutant Human Cancer Cells

Hui-Fang Li, Adam Keeton, Michele Vitolo [...]

Journal of Biomolecular Screening

Select article: Identification of a Putative Tdp1 Inhibitor (CD00509) by in Vitro and Cell-Based Assays

Free access

Research article

First published 2014-12

Identification of a Putative Tdp1 Inhibitor (CD00509) by in Vitro and Cell-Based Assays

Richard A. Dean, Hok Khim Fam, Jianghong An [...]

Journal of Biomolecular Screening

Select article: Neutralizing Antibodies of Botulinum Neurotoxin Serotype A Screened from a Fully Synthetic Human Antibody Phage Display Library

Free access

Research article

First published 2009-09

Neutralizing Antibodies of Botulinum Neurotoxin Serotype A Screened from a Fully Synthetic Human Antibody Phage Display Library

Rui Yu, Shuang Wang, Yun-zhou Yu [...]

Journal of Biomolecular Screening

Select article: Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality

Free access

Research article

First published 2019-6

Novel 2-Benzoyl-6-(2,3-Dimethoxybenzylidene)-Cyclohexenol Confers Selectivity toward Human MLH1 Defective Cancer Cells through Synthetic Lethality

Dedrick Soon Seng Song, Sze Wei Leong, Kwok Wen Ng [...]

Journal of Biomolecular Screening

Select article: CRISPR-GRIT: Guide RNAs with Integrated Repair Templates Enable Precise Multiplexed Genome Editing in the Diploid Fungal Pathogen Candida albicans

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Research article

First published 2024-12

CRISPR-GRIT: Guide RNAs with Integrated Repair Templates Enable Precise Multiplexed Genome Editing in the Diploid Fungal Pathogen Candida albicans

Christopher J. Cotter, Cong T. Trinh

The CRISPR Journal

Select article: In Silico Prediction of Synthetic Lethality by Meta-Analysis of Genetic Interactions,Functions,and Pathways in Yeast and Human Cancer

Open access

Research article

First published 2014

In Silico Prediction of Synthetic Lethality by Meta-Analysis of Genetic Interactions,Functions,and Pathways in Yeast and Human Cancer

Min Wu, Xuejuan Li, Fan Zhang [...]

Cancer Informatics

Select article: A Retrospective Appraisal of the Ability of Animal Tests To Predict Reproductive and Developmental Toxicity in Humans

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Research article

First published 1991-9

A Retrospective Appraisal of the Ability of Animal Tests To Predict Reproductive and Developmental Toxicity in Humans

Thomas A. Marks

International Journal of Toxicology

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