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Articles (105)

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1-10 of 105 results for physiologically based pharmacokinetic modeling

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Select article: Physiologically-Based Pharmacokinetic Modeling *

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First published 1994-1

Physiologically-Based Pharmacokinetic Modeling *

Melvin E. Andersen

Therapeutic Innovation & Regulatory Science

Select article: Physiologically based pharmacokinetic modeling to predict the effect of risperidone on aripiprazole pharmacokinetics in subjects with different CYP2D6 genotypes and individuals with hepatic impairment

Open access

Research article

First published 2024

Physiologically based pharmacokinetic modeling to predict the effect of risperidone on aripiprazole pharmacokinetics in subjects with different CYP2D6 genotypes and individuals with hepatic impairment

Fan Mou, Zhiwei Huang, Yu Cheng [...]

Therapeutic Advances in Drug Safety

Select article: Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment

Open access

Research article

First published 2022-6

Application of Physiologically Based Pharmacokinetic Modeling of Lamotrigine Using PK-Sim in Predicting the Impact of Drug Interactions and Dosage Adjustment

Mohammed Farhan, Prathvi Rani, Fatimazahra Moledina [...]

Journal of Pharmacology and Pharmacotherapeutics

Select article: Predicting drug–drug interactions and optimal dosing of betrixaban with physiologically based pharmacokinetic modeling in patients with renal impairment who were coadministered with P-glycoprotein inhibitors

Open access

Research article

First published 2025-6

Predicting drug–drug interactions and optimal dosing of betrixaban with physiologically based pharmacokinetic modeling in patients with renal impairment who were coadministered with P-glycoprotein inhibitors

Xiaoping Yan, Lirong Xiao, Weina Xie

Journal of International Medical Research

Select article: Physiologically Based Pharmacokinetic Modeling of Cyclohexane as a Tool for Integrating Animal and Human Test Data

Free access

Research article

First published 2009-11

Physiologically Based Pharmacokinetic Modeling of Cyclohexane as a Tool for Integrating Animal and Human Test Data

A. M. Hissink, B. M. Kulig, J. Kruse [...]

International Journal of Toxicology

Select article: Physiological-based pharmacokinetic modeling of endotoxin in the rat

Retricted access

Research article

First published 2014-6

Physiological-based pharmacokinetic modeling of endotoxin in the rat

Joseph C Hutter, Chung S Kim

Toxicology and Industrial Health

Select article: Physiologically-based Pharmacokinetic Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals

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Research article

First published 2010-12

Physiologically-based Pharmacokinetic Modelling for the Reduction of Animal Use in the Discovery of Novel Pharmaceuticals

Simon Thomas

Alternatives to Laboratory Animals

Select article: Chloropentafluorobenzene: Short-Term Inhalation Toxicity,Genotoxicity and Physiologically-Based Pharmacokinetic Model Development

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Research article

First published 1990-12

Chloropentafluorobenzene: Short-Term Inhalation Toxicity,Genotoxicity and Physiologically-Based Pharmacokinetic Model Development

Edwin R. Kinkead, Henry G. Wall, Clifford J. Hixson [...]

Toxicology and Industrial Health

Select article: An introduction to the use of physiologically based pharmacokinetic models in risk assessment

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Research article

First published 1997-08

An introduction to the use of physiologically based pharmacokinetic models in risk assessment

A J Bailer, D A Dankovic

Statistical Methods in Medical Research

Select article: An Approach for Incorporating Tissue Composition Data Into Physiologically Based Pharmacokinetic Models

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Research article

First published 1995-09

An Approach for Incorporating Tissue Composition Data Into Physiologically Based Pharmacokinetic Models

Michael Pelekis, Patrick Poulin, Kannan Krishnan

Toxicology and Industrial Health

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